Zobrazeno 1 - 10
of 123
pro vyhledávání: '"C Theo Verrips"'
Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies
Autor:
Jord C. Stam, Steven de Maat, Dorien de Jong, Mathia Arens, Fenna van Lint, Lavina Gharu, Mark H. van Roosmalen, Rob C. Roovers, Nika M. Strokappe, Ralf Wagner, Alexander Kliche, Hans J. de Haard, Paul M. van Bergen en Henegouwen, Monique Nijhuis, C. Theo Verrips
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of antiretroviral therapy in patient
Externí odkaz:
https://doaj.org/article/ffdba455ddae44ce8e6074f6be3806a7
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Epitope mapping using BMP heterodimers (BMP4/7, BMP2/6 and BMP2/7).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a79b48202f3b0898ee281ba858eac0
https://doi.org/10.1158/1535-7163.22501663
https://doi.org/10.1158/1535-7163.22501663
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Bone morphogenetic proteins (BMP) have important but distinct roles in tissue homeostasis and disease, including carcinogenesis and tumor progression. A large number of BMP inhibitors are available to study BMP function; however, as most of these ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10d83c17fc91e5e3adde4774a0324064
https://doi.org/10.1158/1535-7163.c.6536857.v1
https://doi.org/10.1158/1535-7163.c.6536857.v1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Supplementary file containing Supplementary materials and methods, supplementary figure legends and supplementary references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404265aa745e8b042e9e9f3c4b08f87e
https://doi.org/10.1158/1535-7163.22501660.v1
https://doi.org/10.1158/1535-7163.22501660.v1
Autor:
Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe
Summary of epitope binning experiments of the VHHs and controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973d561ed6d3a9847aeff23646344834
https://doi.org/10.1158/1535-7163.22501657.v1
https://doi.org/10.1158/1535-7163.22501657.v1
Autor:
Robin A. Weiss, C. Theo Verrips
Publikováno v:
Vaccines, Vol 7, Iss 3, p 77 (2019)
Nanobodies or VHH (variable domains of heavy-chain only antibodies) are derived from camelid species such as llamas and camels. Nanobodies isolated and selected through phage display can neutralize a broad range of human immunodeficiency virus type 1
Externí odkaz:
https://doaj.org/article/6f3350587abf441a81b6adf7aff687bf
Autor:
Hannah J. Barbian, Julie M. Decker, Frederic Bibollet-Ruche, Rachel P. Galimidi, Anthony P. West, Gerald H. Learn, Nicholas F. Parrish, Shilpa S. Iyer, Yingying Li, Craig S. Pace, Ruijiang Song, Yaoxing Huang, Thomas N. Denny, Hugo Mouquet, Loic Martin, Priyamvada Acharya, Baoshan Zhang, Peter D. Kwong, John R. Mascola, C. Theo Verrips, Nika M. Strokappe, Lucy Rutten, Laura E. McCoy, Robin A. Weiss, Corrine S. Brown, Raven Jackson, Guido Silvestri, Mark Connors, Dennis R. Burton, George M. Shaw, Michel C. Nussenzweig, Pamela J. Bjorkman, David D. Ho, Michael Farzan, Beatrice H. Hahn
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Broadly cross-reactive neutralizing antibodies (bNabs) represent powerful tools to combat human immunodeficiency virus type 1 (HIV-1) infection. Here, we examined whether HIV-1-specific bNabs are capable of cross-neutralizing distantly relat
Externí odkaz:
https://doaj.org/article/46821e94c4f84dc3b70247c0404d431a
Autor:
Eelko G, Ter Schure, Herman H W, Sillj, Leon J R M, Raeven, Johannes, Boonstra, Arie J, Verkleij, C Theo, Verrips
Publikováno v:
Microbiology (Reading, England). 141(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d41aea1325e8d2f3b3521f8d36d9f95a
https://pubmed.ncbi.nlm.nih.gov/33820123
https://pubmed.ncbi.nlm.nih.gov/33820123
Autor:
David Lutje Hulsik, Ying-ying Liu, Nika M Strokappe, Simone Battella, Mohamed El Khattabi, Laura E McCoy, Charles Sabin, Andreas Hinz, Miriam Hock, Pauline Macheboeuf, Alexandre M J J Bonvin, Johannes P M Langedijk, David Davis, Anna Forsman Quigley, Marlén M I Aasa-Chapman, Michael S Seaman, Alejandra Ramos, Pascal Poignard, Adrien Favier, Jean-Pierre Simorre, Robin A Weiss, C Theo Verrips, Winfried Weissenhorn, Lucy Rutten
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003202 (2013)
The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodie
Externí odkaz:
https://doaj.org/article/bedacc53dae644739bdc70b2ea981c66
Autor:
Milla Summanen, Niko Granqvist, Raimo K Tuominen, Marjo Yliperttula, C Theo Verrips, Johannes Boonstra, Christophe Blanchetot, Elina Ekokoski
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35630 (2012)
Dysregulation of PKCε is involved in several serious diseases such as cancer, type II diabetes and Alzheimer's disease. Therefore, specific activators and inhibitors of PKCε hold promise as future therapeutics, in addition to being useful in resear
Externí odkaz:
https://doaj.org/article/9b60389161564e70bffc909754728330