Zobrazeno 1 - 7
of 7
pro vyhledávání: '"C Tak Hung"'
Publikováno v:
The Journal of Clinical Pharmacology. 60:751-757
Parenteral ketamine has fast-onset antidepressant and antianxiety effects; however, it causes dissociation, hypertension, and tachycardia shortly after dosing. Ketamine's antidepressant effects may be due to active metabolites rather than to ketamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6cc2a9fb0da9a652e1d6c3c661e9c6
https://doi.org/10.1002/jcph.1573
https://doi.org/10.1002/jcph.1573
Autor:
Michelle Marie Lockhart, Holger Weis, Donna Tunnicliff, Sarah Harland, Borje Darpo, Jane Devane, R. S. Crockett, Gavin Cape, John Howes, C. Tak Hung, Meijian Zhou, Lawrence Friedhoff, Noelyn Hung, Fred Lam, Paul Glue
Publikováno v:
Clinical Pharmacology in Drug Development. 5:460-468
Ibogaine is a psychoactive substance that may reduce opioid withdrawal symptoms. This was the first clinical trial of noribogaine, ibogaine's active metabolite, in patients established on methadone opioid substitution therapy (OST). In this randomize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d307c2c1237945aa226f0b88e893451a
https://doi.org/10.1002/cpdd.254
https://doi.org/10.1002/cpdd.254
Autor:
C. Tak Hung, Fred Lam, Noelyn Hung, Gavin Cape, John Howes, Michelle Marie Lockhart, Lawrence Friedhoff, Sarah Harland, Paul Glue, Jane Devane, Holger Weis, Donna Tunnicliff, Andrew R. Gray
Publikováno v:
The Journal of Clinical Pharmacology. 56:960-965
The aim of this study was to switch patients established on methadone opioid substitution therapy (OST) to morphine over 1 week. Subjects established on daily methadone OST (mean dose 60 mg/day) were switched to morphine slow-release capsules, dosed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96dfcf6256f8a8405fee5bc741d581f9
https://doi.org/10.1002/jcph.704
https://doi.org/10.1002/jcph.704
Autor:
Zoe Lenagh‐Glue, Kira Garbe, Paul Glue, Hannah Jakobi, Helen Winter, C. Tak Hung, Alexander Lyudin
Publikováno v:
The Journal of Clinical Pharmacology. 55:680-687
Conversion of ibogaine to its active metabolite noribogaine appears to be mediated primarily by CYP2D6. We compared 168 hours pharmacokinetic profiles of both analytes after a single oral 20 mg dose of ibogaine in 21 healthy subjects who had been pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ce71e747a2987e8c2b35c7d21db3b5
https://doi.org/10.1002/jcph.471
https://doi.org/10.1002/jcph.471
Autor:
Paul, Glue, Gavin, Cape, Donna, Tunnicliff, Michelle, Lockhart, Fred, Lam, Noelyn, Hung, C Tak, Hung, Sarah, Harland, Jane, Devane, R S, Crockett, John, Howes, Borje, Darpo, Meijian, Zhou, Holger, Weis, Lawrence, Friedhoff
Publikováno v:
Clinical pharmacology in drug development. 5(6)
Ibogaine is a psychoactive substance that may reduce opioid withdrawal symptoms. This was the first clinical trial of noribogaine, ibogaine's active metabolite, in patients established on methadone opioid substitution therapy (OST). In this randomize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9118ba2bcaa394fb681bac4cf81e90ed
https://pubmed.ncbi.nlm.nih.gov/27870477
https://pubmed.ncbi.nlm.nih.gov/27870477
Autor:
Paul, Glue, Helen, Winter, Kira, Garbe, Hannah, Jakobi, Alexander, Lyudin, Zoe, Lenagh-Glue, C Tak, Hung
Publikováno v:
Journal of clinical pharmacology. 55(6)
Conversion of ibogaine to its active metabolite noribogaine appears to be mediated primarily by CYP2D6. We compared 168 hours pharmacokinetic profiles of both analytes after a single oral 20 mg dose of ibogaine in 21 healthy subjects who had been pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3158b5e1f3bef49218d2a01a2b47b7b
https://pubmed.ncbi.nlm.nih.gov/25651476
https://pubmed.ncbi.nlm.nih.gov/25651476