Zobrazeno 1 - 3
of 3
pro vyhledávání: '"C T, Hughey"'
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(8)
Secreted IgM is predominantly found as pentameric molecules, but IgM can also be secreted as hexamers by B cell lines. Murine hexamers activate the complement cascade more efficiently than pentamers, but the physiologic significance of hexameric IgM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::205ab7f0500a9fda61836a0fffb4cbbb
https://pubmed.ncbi.nlm.nih.gov/9780180
https://pubmed.ncbi.nlm.nih.gov/9780180
Publikováno v:
Molecular pharmacology. 44(2)
A major mechanism underlying the cytotoxicity of fluoropyrimidine analogs such as 5-fluorouracil and 5-fluoro-2'-deoxyuridine (FdUrd) occurs via the formation of 5-fluoro-2'-deoxyuridylate (FdUMP), a tight-binding inhibitor of thymidylate synthase (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::111e11c084d4be6a974e7321480c053e
https://pubmed.ncbi.nlm.nih.gov/8355668
https://pubmed.ncbi.nlm.nih.gov/8355668
Publikováno v:
Advances in experimental medicine and biology. 339
The human colorectal tumor cell line HCT 116 was resident to the cytotoxic effects of 5-fluorodeoxyuridine (FdUrd). The response to FdUrd was increased only slightly by the presence of 10 microM folinic acid (CF). HCT 116 formed FdUMP and CH2H4PteGlu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93f11b813ffa5cc493db8fd07eab2b3d
https://pubmed.ncbi.nlm.nih.gov/8178730
https://pubmed.ncbi.nlm.nih.gov/8178730