Polymorphism of human telomeric quadruplexes with drugs: a multi-technique biophysical study

Autor: Francesco D'Amico, Claudio Masciovecchio, Alessandro Paciaroni, Heinz Amenitsch, Valeria Libera, Caterina Petrillo, C Sissi, Federico Sebastiani, Francesco Sacchetti, Lucia Comez, Barbara Rossi, Alessandro Gessini, F Bianchi, M. Longo

Publikováno v: PCCP. Physical chemistry chemical physics
22 (2020): 11583–11592. doi:10.1039/d0cp01483d
info:cnr-pdr/source/autori:Comez, L.; Bianchi, F.; Libera, V; Longo, M.; Petrillo, C.; Sacchetti, F.; Sebastiani, F.; D'Amico, F.; Rossi, B.; Gessini, A.; Masciovecchio, C.; Amenitsch, H.; Sissi, C.; Paciaroni, A./titolo:Polymorphism of human telomeric quadruplexes with drugs: a multi-technique biophysical study/doi:10.1039%2Fd0cp01483d/rivista:PCCP. Physical chemistry chemical physics (Print)/anno:2020/pagina_da:11583/pagina_a:11592/intervallo_pagine:11583–11592/volume:22

The human telomeric G-quadruplex structural motif of DNA has come to be known as a new and stimulating target for anticancer drug discovery. Small molecules that interact with G-quadruplex structures in a selective way have gained impressive interest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadf931d1461f83bd6ec0e80b80096f0
https://doi.org/10.1039/d0cp01483d

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Novel asymmetric naphthalenediimide-polyamines conjugates as anticancer agents

Autor: Minarini A, V Tumiatti, A Milelli, C Sissi, ML Greco, Huanzhou, H M Wallace

As the number of cases of cancer increases worldwide there is a need to develop better and more selective anticancer agents. Naphtalenediimide (NDI) scaffold is present in a wide number of anticancer agents which interact with DNA preferentially as i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::197c1d09746e818720353e18cc7444a1
http://hdl.handle.net/11585/143272

Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations

Autor: F. S. Di Leva, P. Zizza, C. Sissi, O. Pinato, A. Cavalli, S. Cosconati, A. Biroccio, PAGANO, BRUNO, AMATO, JUSSARA, MARINELLI, LUCIANA, NOVELLINO, ETTORE, RANDAZZO, ANTONIO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::9365c8ebddc48ae35502a272afa5042b
http://hdl.handle.net/11588/597417

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