Zobrazeno 1 - 10
of 39
pro vyhledávání: '"C Sidhanth"'
Publikováno v:
Genes & Cancer
High grade serous ovarian cancer is characterized by relatively few mutations occurring at low frequency, except in TP53. However other genetic aberrations such as copy number variation alter numerous oncogenes and tumor suppressor genes. Oncogenes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79169cef0f2f910fcb9ff652287c1926
http://europepmc.org/articles/PMC7805537
http://europepmc.org/articles/PMC7805537
Autor:
Velusamy Sridevi, C. Sidhanth, S Sneha, Kanchan Murhekar, Trivadi S. Ganesan, Sundersingh Shirley, Rohit P. Nagare, Rajaraman Swaminathan, S Roopa
Publikováno v:
Cancer Biomarkers. 28:397-408
BACKGROUND There has been variability between laboratories in the identification of cancer stem cells (CSCs) markers for epithelial ovarian cancer (EOC). We have evaluated three new surface markers for EOC to identify CSCs precisely. METHODS Three ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1123846bb6ab3fe2290ddce478aa27
https://doi.org/10.3233/cbm-201463
https://doi.org/10.3233/cbm-201463
Autor:
C. Sidhanth, Trivadi S. Ganesan, S Sneha, Kanchan Murhekar, Sundersingh Shirley, Balaji Ramachandran, P Manasa, Rohit P. Nagare, Syama Krishnapriya, Sadhanandhan Bindhya, Pushpa Vishwanathan
Publikováno v:
Angiogenesis. 22:441-455
The origin of blood and lymphatic vessels in high-grade serous adenocarcinoma of ovary (HGSOC) is uncertain. We evaluated the potential of cancer stem cells (CSCs) in HGSOC to contribute to their formation. Using spheroids as an in vitro model for CS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35aa0649fe4352bc4d1f1c137c2f4ee
https://doi.org/10.1007/s10456-019-09669-x
https://doi.org/10.1007/s10456-019-09669-x
Autor:
C, Sidhanth, S, Bindhya, S, Krishnapriya, P, Manasa, A, Shabna, J, Alifia, C, Patole, V, Kumar, M, Garg, T S, Ganesan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1870:140768
The gene for receptor tyrosine kinase ErbB2 is amplified in breast and ovarian tumours. The linear pathway by which signals are transduced through ErbB2 are well known. However, second generation questions that address spatial aspects of signaling re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7534e5eb932497edbff578c3243382
https://doi.org/10.1016/j.bbapap.2022.140768
https://doi.org/10.1016/j.bbapap.2022.140768
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 138:106051
Ovarian cancer recurs despite advances in treatment and is due to drug resistance. The persistence of cancer stem cells (CSCs) is one of the causes. It has been challenging to maintain CSCs long term in culture from primary malignant cells. Reprogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e396f05b82cd1e637e0ebc01e71aa2
https://doi.org/10.1016/j.biocel.2021.106051
https://doi.org/10.1016/j.biocel.2021.106051
Publikováno v:
Cancer Research. 81:LB195-LB195
Ovarian cancer is the most common cause of death due to gynaecological cancer. Comprehensive genomic analysis by the TCGA consortium of HGSOC (high grade serous ovarian cancer) has not identified mutated genes (except p53 and BRCA) at sufficient freq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd51219cfae79b151e36c16f75644cfd
https://doi.org/10.1158/1538-7445.am2021-lb195
https://doi.org/10.1158/1538-7445.am2021-lb195
Publikováno v:
Cancer Immunology, Immunotherapy. 66:1383-1398
Monoclonal antibodies have been extensively used to treat malignancy along with routine chemotherapeutic drugs. Chemotherapy for metastatic cancer has not been successful in securing long-term remission of disease. This is in part due to the resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228c128270e99e14192b59e05b73e088
https://doi.org/10.1007/s00262-017-2049-0
https://doi.org/10.1007/s00262-017-2049-0
Autor:
C. Sidhanth, Trivadi S. Ganesan, S. Krishna Priya, S. Bindhya, P Manasa, V S. Sneha, Rohit P. Nagare
Publikováno v:
International Journal of Cancer. 139:729-735
The conventional view of tumour vascularization is that tumours acquire their blood supply from neighbouring normal stroma. Additional methods of tumour vascularization such as intussusceptive angiogenesis, vasculogenic mimicry, vessel co-option and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c0bfab5cc768c7f8c3f0a4ae723148
https://doi.org/10.1002/ijc.30067
https://doi.org/10.1002/ijc.30067
Publikováno v:
The international journal of biochemistrycell biology. 107
Induced pluripotent stem cells are derived from adult somatic cells by ectopic expression of stem cell factors OCT4, SOX2, MYC and KLF4. These cells have characteristic features similar to embryonic stem cells. Although there exists in vitro and in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ff27ca84afde90d2efc1d867520dbe
https://pubmed.ncbi.nlm.nih.gov/30557622
https://pubmed.ncbi.nlm.nih.gov/30557622
Autor:
Trivadi S. Ganesan, S. Bindhya, C. Sidhanth, S Sneha, P Manasa, Manoj Garg, Syama Krishnapriya, Rohit P. Nagare
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 96(3)
ErbB2 is an important receptor tyrosine kinase and a member of the ErbB family. Although it does not have a specific ligand, it transmits signals downstream by heterodimerization with other receptors in the family. It plays a major role in a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dc6f5fd50f9de4c3ee95b67d86f944
https://pubmed.ncbi.nlm.nih.gov/29792724
https://pubmed.ncbi.nlm.nih.gov/29792724