Zobrazeno 1 - 10
of 145
pro vyhledávání: '"C Shakespeare"'
Autor:
Victor M. Rivera, Tim Clackson, Frank Wang, William C. Shakespeare, Narayana I. Narasimhan, Qurish K. Mohemmad, Scott Wardwell, Lauren Moran, Matthew J. Wong, Joseph M. Gozgit
Members of the fibroblast growth factor receptor family of kinases (FGFR1–4) are dysregulated in multiple cancers. Ponatinib (AP24534) is an oral multitargeted tyrosine kinase inhibitor being explored in a pivotal phase II trial in patients with ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f39a803ac9fd251dac4bfc2513c8a34
https://doi.org/10.1158/1535-7163.c.6536118
https://doi.org/10.1158/1535-7163.c.6536118
Autor:
Victor M. Rivera, Xiaotian Zhu, Kwok-kin Wong, Shengwu Liu, Robert J. Griffin, Johara Chouitar, Michael Fitzgerald, William C. Shakespeare, David Dalgarno, Tim Clackson, Narayana I. Narasimhan, Biplab Das, Stephan G. Zech, Matthew T. Greenfield, Feng Li, Yongbo Hu, Wei-Sheng Huang, Sen Zhang, Yaoyu Ning, Sara Nadworny, Scott D. Wardwell, Shuai Li, Alexandra E. Gould, Theresa E. Baker, Sylvie Vincent, Francois Gonzalvez
Most EGFR exon 20 insertion (EGFRex20ins) driver mutations in non–small cell lung cancer (NSCLC) are insensitive to approved EGFR tyrosine kinase inhibitors (TKI). To address the limitations of existing therapies targeting EGFR-mutated NSCLC, moboc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1233d4a09c246c7e577a052bb61a6464
https://doi.org/10.1158/2159-8290.c.6549370.v1
https://doi.org/10.1158/2159-8290.c.6549370.v1
Autor:
Victor M. Rivera, Tim Clackson, Frank Wang, William C. Shakespeare, Narayana I. Narasimhan, Qurish K. Mohemmad, Scott Wardwell, Lauren Moran, Matthew J. Wong, Joseph M. Gozgit
PDF file - 89K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204d870cea2dd90df5ac2f4c153a4b22
https://doi.org/10.1158/1535-7163.22499316.v1
https://doi.org/10.1158/1535-7163.22499316.v1
Autor:
Victor M. Rivera, Tim Clackson, Frank Wang, William C. Shakespeare, Narayana I. Narasimhan, Qurish K. Mohemmad, Scott Wardwell, Lauren Moran, Matthew J. Wong, Joseph M. Gozgit
PDF file - 457K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73384c8e889704535b231a4ea75b9e5d
https://doi.org/10.1158/1535-7163.22499319.v1
https://doi.org/10.1158/1535-7163.22499319.v1
Autor:
Victor M. Rivera, Tim Clackson, Frank Wang, William C. Shakespeare, Narayana I. Narasimhan, Qurish K. Mohemmad, Scott Wardwell, Lauren Moran, Matthew J. Wong, Joseph M. Gozgit
PDF file - 73K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816075e43e2bad27f4b2ca0728a4e436
https://doi.org/10.1158/1535-7163.22499313
https://doi.org/10.1158/1535-7163.22499313
Autor:
Victor M. Rivera, Xiaotian Zhu, Kwok-kin Wong, Shengwu Liu, Robert J. Griffin, Johara Chouitar, Michael Fitzgerald, William C. Shakespeare, David Dalgarno, Tim Clackson, Narayana I. Narasimhan, Biplab Das, Stephan G. Zech, Matthew T. Greenfield, Feng Li, Yongbo Hu, Wei-Sheng Huang, Sen Zhang, Yaoyu Ning, Sara Nadworny, Scott D. Wardwell, Shuai Li, Alexandra E. Gould, Theresa E. Baker, Sylvie Vincent, Francois Gonzalvez
Supplementary Tables (S1-6) and Figures (S1-6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b1686b17282cc4afaa22ed044b1306
https://doi.org/10.1158/2159-8290.22540399
https://doi.org/10.1158/2159-8290.22540399
Autor:
Victor M. Rivera, William C. Shakespeare, David Dalgarno, Tim Clackson, Xiaotian Zhu, Juan Miret, Frank Wang, Narayana Narasimhan, Emily Ye, Hyun Gyung Jang, Qurish Mohemmad, Yihan Wang, Dong Zou, Shuangying Liu, Wei-Sheng Huang, Lauren Moran, Lindsey Eichinger, Youngchul Song, David Miller, Scott D. Wardwell, Yaoyu Ning, Jeff Keats, Tianjun Zhou, Sara Nadworny, Rachel Squillace, Rana Anjum, Sen Zhang
Purpose: Non–small cell lung cancers (NSCLCs) harboring ALK gene rearrangements (ALK+) typically become resistant to the first-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI) crizotinib through development of secondary r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5126f7a2057f9c47635f6496d280ebf0
https://doi.org/10.1158/1078-0432.c.6525524.v1
https://doi.org/10.1158/1078-0432.c.6525524.v1
Autor:
Victor M. Rivera, William C. Shakespeare, David Dalgarno, Tim Clackson, Xiaotian Zhu, Juan Miret, Frank Wang, Narayana Narasimhan, Emily Ye, Hyun Gyung Jang, Qurish Mohemmad, Yihan Wang, Dong Zou, Shuangying Liu, Wei-Sheng Huang, Lauren Moran, Lindsey Eichinger, Youngchul Song, David Miller, Scott D. Wardwell, Yaoyu Ning, Jeff Keats, Tianjun Zhou, Sara Nadworny, Rachel Squillace, Rana Anjum, Sen Zhang
Supplementary Table 1. Brigatinib in vitro activity (IC50s) in a kinase panel (N=289); Supplementary Figure 1. Chemical structures of brigatinib, crizotinib, ceritinib, and alectinib; Supplementary Figure 2. Brigatinib-mediated inhibition of native o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6bdb6961073a5b3e650ddfb94203a6
https://doi.org/10.1158/1078-0432.22463789.v1
https://doi.org/10.1158/1078-0432.22463789.v1
Akademický článek
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Autor:
Christopher C. Shakespeare, Andrew M. Weller, Dipna A. Patel, Elizabeth C. Landis, Robert B. Chevalier, Edward J. Soares
Publikováno v:
The Journal of Physical Chemistry C. 124:26851-26863
We investigated the stability, ordering, and composition of mixed self-assembled monolayers (SAMs) on nanoporous gold surfaces formed by dealloying silver–gold leaf. We characterized surface featur...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a630ab837fcd2211c9d2a38716d774c1
https://doi.org/10.1021/acs.jpcc.0c08685
https://doi.org/10.1021/acs.jpcc.0c08685
