Zobrazeno 1 - 10
of 237
pro vyhledávání: '"C Semino"'
Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model
Autor:
ML Sennett,, JM Friedman, BS Ashley, BD Stoeckl, JM Patel, M Alini, M Cucchiarini, D Eglin, H Madry, A Mata, C Semino, MJ Stoddart, B Johnstone, FT Moutos, BT Estes, F Guilak,, RL Mauck, GR Dodge
Publikováno v:
European Cells & Materials, Vol 41, Pp 40-51 (2021)
The repair of focal cartilage defects remains one of the foremost issues in the field of orthopaedics. Chondral defects may arise from a variety of joint pathologies and left untreated, will likely progress to osteoarthritis. Current repair technique
Externí odkaz:
https://doaj.org/article/d420437fbd064e1bae7368d21c40afeb
Publikováno v:
Computers in Biology and Medicine. 77:249-260
Cell clustering and aggregation are fundamental processes in the development of several tissues and the progression of many diseases. The formation of these aggregates also has a direct impact on the oxygen concentration in their surroundings due to
Akademický článek
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Autor:
C. Semino-Mora, S. H. Subramony, Mark R. Davis, Nigel G. Laing, Peter C. Scacheri, Eric P. Hoffman, A. Senchak, V. V. Vedanarayanan, Jonathan D. Fratkin
Publikováno v:
Neurology. 55:1689-1696
Background: Central core disease (CCD) and nemaline rod myopathy are generally considered two genetically and histologically distinct disorders. CCD is defined by the presence of well-demarcated round cores within most myofibers. Nemaline rod myopath
Autor:
G Pietra, M Guastella, C. Chiarugi, Lorenzo Borgognoni, G Melioli, Umberto Maria Reali, C Semino, L. Martini
Publikováno v:
Melanoma Research. 8:72-82
A pilot study was set up in order to evaluate the feasibility and safety of infusing in vitro expanded tumour-infiltrating lymphocytes (TILs) and recombinant interleukin-2 (rIL-2) in a group of patients with advanced melanoma after radical resection
Akademický článek
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Autor:
C. Viscoli, C. Bighin, G. Pietra, Giovanni Melioli, M. Bergaglio, C. Semino, Mario Roberto Sertoli, Riccardo Rosso, L. Del Mastro, M. Venturini, A. Signorini, A. Lambiase, G. Bertelli, Sergio Bertoglio
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 12(4)
Summary Background The majority of high-dose chemotherapy (HDC)-related complications results from bone marrow aplasia, but the graft infusion per se may cause adverse reactions due to the injection of both dimethyl sulfoxide (DMSO) and cell lysis pr
Autor:
K Y, Park, M C, Dalakas, C, Semino-Mora, H S, Lee, S, Litvak, K, Takeda, V J, Ferrans, L G, Goldfarb
Publikováno v:
Clinical genetics. 57(6)
Desmin myopathy is a familial or sporadic disorder characterized by intracytoplasmic accumulation of desmin in the muscle cells. We and others have previously identified desmin gene mutations in patients with familial myopathy, but close to 45% of th
Publikováno v:
Tissue antigens. 55(3)
Interferons upregulate the expression of HLA class I antigens on cancer cells. Nevertheless, little is known about the panel of HLA class I antigen-associated peptides presented by recombinant alpha-interferon (r(alpha)-IFN)-treated cells. For this r
Autor:
C, Semino, L, Martini, P, Queirolo, G, Cangemi, R, Costa, A, Alloisio, G, Ferlazzo, M R, Sertoli, U M, Reali, G B, Ratto, G, Melioli
Publikováno v:
Anticancer research. 19(6C)
Adoptive immunotherapy (AI) of cancer, based upon the injection of in vitro manipulated autologous lymphocytes is still in an experimental phase. Our group started different clinical trials of AI in early 1990, and, at present, some specific targets