Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C S Weikel"'
Publikováno v:
The American Journal of Medicine. 93:163-170
To describe the clinical, radiographic, and laboratory features of sinus disease in human immunodeficiency virus (HIV)-infected individuals.Seventy-two patients with a history of sinusitis identified from 1,461 consecutive admissions (667 patients) t
Publikováno v:
FEBS Letters. 274:199-202
STa, the heat-stable enterotoxin of Escherichiu coli , stimulates membrane-bound guanylate cyclase in enterocytes, elevates cyclic GMP. and results in intestinal secretion of ions and fluid. Using the T84 colon carcinoma cell line as a model, Weikel
Publikováno v:
Infection and Immunity. 58:1402-1407
We examined the effect of protein kinase C (PKC) activation on the cyclic GMP response to heat-stable enterotoxin (STa) in a colonic carcinoma intestinal epithelial cell line, T84 cells. Our results demonstrate that the active phorbol ester analog, p
Publikováno v:
Infection and immunity. 60(2)
Bacteroides fragilis has been associated with causation of diarrheal disease in livestock and humans. To date, conventional tissue culture and animal assays used to detect the biologic activity of bacterial enterotoxins have failed with enterotoxigen
Autor:
C. S. Weikel, James H. Grendell, P. Basuk, C. M. Wilcox, A. E. Read, Chris E. Forsmark, Richard P. Rood, M. Wittner, John P. Cello, L. Weiss, D. Simon, Colette Beaumont, J. A. Satow
Publikováno v:
Annals of internal medicine. 115(9)
Objective To determine the efficacy and safety of octreotide for treatment of refractory, profuse diarrhea in patients with the acquired immunodeficiency syndrome (AIDS). Design A prospective, open-label study. Setting Inpatient metabolic units of fo
Publikováno v:
The American journal of tropical medicine and hygiene. 44(1)
In order to develop an experimental model of symptomatic cryptosporidiosis in an immunosuppressed mammal, we investigated the pathophysiology of infection with Cryptosporidium and the humoral and cellular host responses in rnu/rnu (athymic) rats and
Publikováno v:
Journal of Clinical Investigation. 76:2430-2435
Microbial toxins act through cyclic nucleotide dependent (cAMP or cGMP) or cyclic nucleotide independent pathways to cause intestinal ion secretion. To explore the calcium dependent, cyclic nucleotide independent pathway that is postulated to involve
Publikováno v:
Journal of Infectious Diseases. 153:893-901
Escherichia coli may produce a heat-labile enterotoxin (LT) or two heat-stable enterotoxins (STa, STb). STb consistently causes secretion in vivo in 5-hr weaned-pig intestinal loops (P less than .0001). In Ussing chambers in vitro, crude culture filt
Autor:
Erik L. Hewlett, Myron M. Levine, Richard L. Guerrant, K T Tiemens, C S Weikel, S A Long-Krug
Publikováno v:
Infection and Immunity. 46:612-614
Although most enteropathogenic Escherichia coli strains do not produce recognized enterotoxins, we wished to examine whether they produce any factors like heat-stable enterotoxin b or cholera toxin active subunits that might be missed by conventional
Publikováno v:
Infection and immunity. 52(1)
Escherichia coli strains produce at least two heat-stable enterotoxins, STa and STb. STa is well known to be important in the pathogenesis of human diarrheal disease; the role of STb has not been defined. Fifty-two E. coli strains recovered from huma