Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C S Tripp"'
Publikováno v:
The Journal of Immunology. 155:3427-3432
During a secondary immune response to Listeria monocytogenes (LM), the production of IFN-gamma was still required for resistance, but it was considerably less dependent on IL-12 production. When IL-12 was neutralized in vivo using specific hamster an
Publikováno v:
Journal of Clinical Investigation. 95:1628-1634
The presence of soluble antigen-antibody complexes renders mice highly susceptible to infection with the intracellular pathogen Listeria monocytogenes. In this report we show that this inhibition is manifest at the level of the innate immune response
Publikováno v:
The Journal of Immunology. 152:1883-1887
Interleukin-12 (IL-12) is necessary for the production of IFN-gamma by NK cells during the generation of innate immunity and by T cells for the development of the Th1 response during specific cell-mediated immunity. Here we demonstrate that the endog
Autor:
Q K, Huynh, H, Boddupalli, S A, Rouw, C M, Koboldt, T, Hall, C, Sommers, S D, Hauser, J L, Pierce, R G, Combs, B A, Reitz, J A, Diaz-Collier, R A, Weinberg, B L, Hood, B F, Kilpatrick, C S, Tripp
Publikováno v:
The Journal of biological chemistry. 275(34)
Nuclear factor kappa B (NF-kappaB) is a ubiquitous, inducible transcription factor that regulates the initiation and progression of immune and inflammatory stress responses. NF-kappaB activation depends on phosphorylation and degradation of its inhib
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(7)
During a secondary immune response to Listeria monocytogenes (LM), the production of IFN-gamma was still required for resistance, but it was considerably less dependent on IL-12 production. When IL-12 was neutralized in vivo using specific hamster an
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(4)
Interleukin-12 (IL-12) is necessary for the production of IFN-gamma by NK cells during the generation of innate immunity and by T cells for the development of the Th1 response during specific cell-mediated immunity. Here we demonstrate that the endog
Publikováno v:
Journal of Biological Chemistry. 260:5895-5898
The regulation of arachidonic acid conversion by the 5-lipoxygenase and the cyclooxygenase pathways in mouse peritoneal macrophages has been studied using particulate and soluble agonists. Particulate agonists, zymosan and latex, stimulated the produ
Publikováno v:
The Journal of Immunology. 140:3140-3143
Macrophages isolated from liver granulomas of mice infected with Schistosoma mansoni for 8 or 20 wk synthesize predominantly thromboxane A2 with smaller amounts of the PGE2 and PGI2. There is no physiologic production of leukotrienes, as determined b
Publikováno v:
The Journal of Immunology. 137:3915-3920
We have examined the physiological effects of both exogenously and endogenously produced arachidonic acid metabolites on the expression of class II histocompatibility molecules in murine macrophages. This report shows that both a stable PGI2 analog a
Publikováno v:
The Journal of clinical investigation. 79(2)
This paper demonstrates that in the presence of indomethacin, a cyclooxygenase inhibitor, 100% of the mice died when infected with live Listeria, whereas none of the animals died in the absence of the drug. The death of the animals correlated with th