Zobrazeno 1 - 10
of 146
pro vyhledávání: '"C S Raine"'
Publikováno v:
The Journal of Immunology. 157:941-949
Previous studies have detected gamma delta T cells in multiple sclerosis and experimental allergic encephalomyelitis (EAE) lesions but their role remains obscure. In the present study, we assessed gamma delta T cell dynamics and distribution in splee
Publikováno v:
The Journal of Immunology. 154:3548-3556
The factors that contribute to disease progression in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are not known. In this study, we have tested the hypothesis that inflammation in the central nervous
Publikováno v:
The Journal of Immunology. 154:450-458
Experimental allergic encephalomyelitis (EAE) is an autoimmune disease characterized by central nervous system inflammation and demyelination. Retinoids regulate cell differentiation and growth by binding to and activating retinoic acid receptors, wh
Publikováno v:
The Journal of Immunology. 152:2051-2059
Experimental allergic encephalomyelitis (EAE) is an autoimmune disease that can be induced by the adoptive transfer of CD4, myelin basic protein (MBP)-specific T cells. Superantigens activate T cells expressing appropriate TCR V genes. In this study,
Publikováno v:
Neurology. 72(19)
We read the article by Lindsey et al.1 with interest, where the authors refer to our findings on the same subject.2 They repeated our experiments and concluded with a different interpretation that staining with anti-Nogo A Ab in CSF of patients with
Publikováno v:
The Journal of Immunology. 147:1522-1529
The cytotoxic effect of recombinant human cytokines was tested on glial cells cultured from mature bovine brain. Lymphotoxin (LT) and TNF induced injury to oligodendrocytes in a time and dose-dependent fashion. The other cytokines tested, IFN-gamma,
Publikováno v:
The Journal of Immunology. 146:3012-3017
Experimental allergic encephalomyelitis (EAE) is an autoimmune disease characterized by inflammation and demyelination in the central nervous system. The effect of the immunosuppressive molecule transforming growth factor-beta, (TGF-beta 1) on chroni
Publikováno v:
The Journal of Immunology. 144:129-135
The effect of cytokines on astrocytes cultured from mature bovine brain was determined both in a serum-containing medium and in a chemically-defined medium. The results showed that in serum-free medium, human TNF and, to a lesser degree, IL-6 and lym
Autor:
C. S. Raine, R. Nitsch, Frauke Zipp, K. Müller-Wielsch, C. Schmitz, O. Aktas, Friedemann Paul, J. Vogt
Publikováno v:
Klinische Neurophysiologie. 38
Fragestellung: Kommt es bei der Multiplen Sklerose (MS) zu einem Untergang spinaler Motoneurone, und wenn ja, in welchem Ausmas? Hintergrund: Nachdem die MS lange Zeit als ausschlieslich oder uberwiegend entzundliche und demyelinisierende Erkrankung
Publikováno v:
Journal of neural transmission. Supplementum. (60)
Glutamate excitotoxicity mediated by the AMPA/kainate-type of glutamate receptors is known not only to damage neurons but also the myelin-producing cell of the central nervous system (CNS), the oligodendrocyte. In Multiple Sclerosis (MS), myelin, oli