Targeted discovery proteomics to identify clinical phenotypes in heart failure with preserved ejection fraction: a proteomics substudy of VITALITY-HFpEF

Autor: C Defilippi, S J Shah, W Alemayehu, C S P Lam, J Butler, S Reimann, C M O'Connor, P Shah, C M Westerhout, P W Armstrong

Publikováno v: European Heart Journal. 43

Background Heart failure with preserved ejection fraction (HFpEF) is a heterogenous syndrome that may emerge from overlapping systemic processes associated with several medical co-morbidities, often within an inflammatory milieu. Identification of un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1d45ac8931b70e0b8d478370b4f596b
https://doi.org/10.1093/eurheartj/ehac544.781

Tissue factor cytoplasmic domain exacerbates post-infarct left ventricular remodeling via orchestrating cardiac inflammation and angiogenesis

Autor: J W Wang, S Y Chong, O Zharkova, S M J M Yatim, X Wang, X C Lim, C Huang, C Y Tan, J Jiang, H H Versteeg, M Dewerchin, P Carmeliet, C S P Lam, M Y Chan

Publikováno v: European Heart Journal. 42

Introduction The coagulation protein tissue factor (TF) regulates inflammation and angiogenesis via its cytoplasmic domain in infection, cancer and diabetes. While TF is highly abundant in the heart and implicated in cardiac injuries and dysfunction,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4655ba6167e09a6937ab24ff165dd46
https://doi.org/10.1093/eurheartj/ehab724.3249

2397Air pollution and mortality in the tropics

Autor: S Ma, Anders Sahlén, Y X Ng, V Lee, K K Yeo, J Yap, C S P Lam

Publikováno v: European Heart Journal. 39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e8613184b4f0c204dc75d73c4625eec
https://doi.org/10.1093/eurheartj/ehy565.2397

Pilot survey of the diagnosis and management of heart failure in primary care: a Singaporean perspective

Autor: S R, Soon, R, Yong, Z H, Chew, J M J, Lee, C S P, Lam

Publikováno v: Annals of the Academy of Medicine, Singapore. 33(4)

The diagnosis and management of congestive heart failure at the primary care level is difficult. Despite advances in medical therapy, namely angiotensin-converting enzyme inhibitors and beta-blockers, congestive heart failure remains a common cause o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8320dd95daa936789d9ff6cc5ead9e9
https://pubmed.ncbi.nlm.nih.gov/15329750

Sex differences in efficacy of pharmacological therapies in heart failure with reduced ejection fraction: a meta-analysis.

Autor: Danielson C; National Heart Centre Singapore, 5 Hospital Drive, Level 10, Singapore, 169609, Singapore.; Department of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, SE-221 85, Sweden., Lileikyte G; National Heart Centre Singapore, 5 Hospital Drive, Level 10, Singapore, 169609, Singapore.; Department of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, SE-221 85, Sweden., Ouwerkerk W; National Heart Centre Singapore, 5 Hospital Drive, Level 10, Singapore, 169609, Singapore.; Department of Dermatology, Amsterdam UMC, University of Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, The Netherlands., S P Lam C; National Heart Centre Singapore, 5 Hospital Drive, Level 10, Singapore, 169609, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Erlinge D; Department of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, SE-221 85, Sweden., Teng TK; National Heart Centre Singapore, 5 Hospital Drive, Level 10, Singapore, 169609, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; School of Allied Health, University of Western Australia, Perth, Australia.

Publikováno v: ESC heart failure [ESC Heart Fail] 2022 Aug; Vol. 9 (4), pp. 2753-2761. Date of Electronic Publication: 2022 May 23.