Zobrazeno 1 - 10
of 67
pro vyhledávání: '"C Robin, Hiley"'
Autor:
Lyudmyla Borysova, Kim A. Dora, Josh F. Smith, C. Robin Hiley, Hamish A.L. Lemmey, Christopher J. Garland
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
Endothelial dysfunction in small arteries is a ubiquitous, early feature of cardiovascular disease, including hypertension. Dysfunction reflects reduced bioavailability of endothelium-derive
Endothelial dysfunction in small arteries is a ubiquitous, early feature of cardiovascular disease, including hypertension. Dysfunction reflects reduced bioavailability of endothelium-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f63563e6ba8ee0f1b90dca07854baee
https://doi.org/10.1161/hypertensionaha.120.15491
https://doi.org/10.1161/hypertensionaha.120.15491
Autor:
C. Robin Hiley, Yousuf M AlSuleimani
Publikováno v:
European Journal of Pharmacology. 702:1-11
The actions of the anandamide-like mono-unsaturated fatty acid oleoylethanolamide (OEA) were first linked to satiety and control of food intake and recently reported to relax resistance vessels. This study characterizes its vasorelaxant mechanisms. V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd9134cb96014f61b0bd801f5db6f51
https://doi.org/10.1016/j.ejphar.2013.01.006
https://doi.org/10.1016/j.ejphar.2013.01.006
Publikováno v:
British Journal of Pharmacology. 164:839-852
Our view of the endothelium was transformed around 30 years ago, from one of an inert barrier to that of a key endocrine organ central to cardiovascular function. This dramatic change followed the discoveries that endothelial cells (ECs) elaborate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff986136cb10f0a7d5501e8eed21d58c
https://doi.org/10.1111/j.1476-5381.2010.01148.x
https://doi.org/10.1111/j.1476-5381.2010.01148.x
Autor:
Pui Man Hoi, C. Robin Hiley
Publikováno v:
Cardiovascular Drug Reviews. 25:46-60
Oleamide (cis-9,10-octadecenoamide), a fatty acid primary amide discovered in the cerebrospinal fluid of sleep-deprived cats, has a variety of actions that give it potential as a signaling molecule, although these actions have not been extensively in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d99da0bb7381c7bedcabc5cf13f8ff
https://doi.org/10.1111/j.1527-3466.2007.00004.x
https://doi.org/10.1111/j.1527-3466.2007.00004.x
Autor:
C. Robin Hiley, Pui Man Hoi
Publikováno v:
British Journal of Pharmacology. 147:560-568
Oleamide (cis-9-octadecenoamide) exhibits some cannabimimetic responses despite its low affinities at the currently known cannabinoid receptors. Here we have investigated whether or not it is a vasorelaxant in rat small mesenteric arteries. Oleamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b50d3328910e7bf89f0fa9264cf2ffa
https://doi.org/10.1038/sj.bjp.0706643
https://doi.org/10.1038/sj.bjp.0706643
Publikováno v:
Trends in Pharmacological Sciences. 27:1-4
Increasing evidence suggests that some cannabinoids mediate their effects independently of the known cannabinoid CB(1) and CB(2) receptors. Two recently published patents indicate that several cannabinoid receptor ligands also bind to the orphan G-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2403239db8872e54b6ee2f19e9414011
https://doi.org/10.1016/j.tips.2005.11.003
https://doi.org/10.1016/j.tips.2005.11.003
Publikováno v:
British Journal of Pharmacology. 146:809-816
Although the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide share a similar pharmacology, 2-AG reportedly limits myocardial ischaemia–reperfusion injury whereas anandamide does not. We therefore investigated whether or not anandamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c908261098bd6a3d3e1c665c1f7609
https://doi.org/10.1038/sj.bjp.0706391
https://doi.org/10.1038/sj.bjp.0706391
Autor:
W-S Vanessa Ho, C. Robin Hiley
Publikováno v:
Journal of Pharmacy and Pharmacology. 56:869-875
Virodhamine is a recently identified novel endocannabinoid. Cannabinoids may evoke vasorelaxation through novel receptors in the vasculature and/or through release of vasodilator peptides from sensory nerve endings. Virodhamine induced endothelium-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b8640c253df1f6373079e95c1d2e2e
https://doi.org/10.1211/0022357023682
https://doi.org/10.1211/0022357023682
Autor:
C. Robin Hiley, W S Vanessa Ho
Publikováno v:
British Journal of Pharmacology. 139:585-597
Three cannabinoid receptor agonists, anandamide (CB1 receptor-selective) and the aminoalkyl-indoles, JWH 015(2-methyl-1-propyl-1H-indol-3-yl)-1-napthalenylmethanone; (CB2 receptor-selective), R-(+)-WIN 55,212-2 (R-(+)-[2,3-dihydro-5-methyl-3-(4-morph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d347324579fb6e2cecb3c57f1c2cfa0
https://doi.org/10.1038/sj.bjp.0705280
https://doi.org/10.1038/sj.bjp.0705280
Publikováno v:
British Journal of Pharmacology. 139:661-671
Vasorelaxation and hyperpolarization of endothelial cells by adenosine 5′-[β-thio]diphosphate (ADPβS) and adenosine 5′-[γ-thio]triphosphate (ATPγS) were studied in rat-isolated mesenteric artery. Effects from stimulation of P2X receptors were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::258f1a4a1dd5a65a4a3b978dc96e9e4b
https://doi.org/10.1038/sj.bjp.0705271
https://doi.org/10.1038/sj.bjp.0705271