Zobrazeno 1 - 10
of 639
pro vyhledávání: '"C Reading"'
Autor:
Melkamu B. Tessema, Shouya Feng, Daniel Enosi Tuipulotu, Rubaiyea Farrukee, Chinh Ngo, Catarina Gago da Graça, Masahiro Yamomoto, Daniel T. Utzschneider, Andrew G. Brooks, Sarah L. Londrigan, Si Ming Man, Patrick C. Reading
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Dynamin-like GTPase proteins, including myxoma (Mx) and guanylate-binding proteins (GBPs), are among the many interferon stimulated genes induced following viral infections. While studies report that human (h)GBPs inhibit different viruses i
Externí odkaz:
https://doaj.org/article/ceb6b8a352e24988803a092b6ca91a95
Autor:
Rubaiyea Farrukee, Lara S. U. Schwab, James B. Barnes, Andrew G. Brooks, Sarah L. Londrigan, Gunther Hartmann, Thomas Zillinger, Patrick C. Reading
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Myxovirus resistance (Mx) proteins are products of interferon stimulated genes (ISGs) and Mx proteins of different species have been reported to mediate antiviral activity against a number of viruses, including influenza A viruses (IAV). Fer
Externí odkaz:
https://doaj.org/article/4f11a884256f454cb786cbb7c1250c09
Autor:
Nathalie A J Verzele, Brendon Y Chua, Kirsty R Short, Aung Aung Kywe Moe, Isaac N Edwards, Helle Bielefeldt-Ohmann, Katina D Hulme, Ellesandra C Noye, Marcus Z W Tong, Patrick C Reading, Matthew W Trewella, Stuart B Mazzone, Alice E McGovern
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011635 (2024)
Influenza A virus (IAV) is a common respiratory pathogen and a global cause of significant and often severe morbidity. Although inflammatory immune responses to IAV infections are well described, little is known about how neuroimmune processes contri
Externí odkaz:
https://doaj.org/article/0301a849f93546c297d1e30175947711
Autor:
Pin Shie Quah, Bang M. Tran, Vincent D.A. Corbin, Jessie J.-Y. Chang, Chinn Yi Wong, Andrés Diaz-Méndez, Carol A. Hartley, Weiguang Zeng, Eric Hanssen, Zlatan Trifunovic, Patrick C. Reading, David C. Jackson, Elizabeth Vincan, Lachlan J.M. Coin, Georgia Deliyannis
Publikováno v:
Organoids, Vol 2, Iss 2, Pp 82-101 (2023)
Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in feedlot cattle. Bovine herpesvirus-1 (BHV-1) is one of the main culprits of BRD; however, research on BHV-1 is hampered by the lack of suitable models for infection a
Externí odkaz:
https://doaj.org/article/ed4322c03eea4e6aaacc8409cdb74018
Autor:
Keith J. Chappell, Francesca L. Mordant, Alberto A. Amarilla, Naphak Modhiran, Benjamin Liang, Zheyi Li, Danushka K. Wijesundara, Julia A. Lackenby, Paul Griffin, Jillian K. Bennet, Luca Hensen, Wuji Zhang, Thi H.O. Nguyen, Mai H. Tran, Peter Tapley, James Barnes, Patrick C. Reading, Katherine Kedzierska, Charani Ranasinghe, Kanta Subbarao, Daniel Watterson, Paul R. Young, Trent P. Munro
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104842- (2023)
Summary: Background: We previously demonstrated the safety and immunogenicity of an MF59-adjuvanted COVID-19 vaccine based on the SARS-CoV-2 spike glycoprotein stabilised in a pre-fusion conformation by a molecular clamp using HIV-1 glycoprotein 41 s
Externí odkaz:
https://doaj.org/article/87b8ffb3adb84cda943c56e9895eaebd
Autor:
Peter Speck, Jason Mackenzie, Rowena A. Bull, Barry Slobedman, Heidi Drummer, Johanna Fraser, Lara Herrero, Karla Helbig, Sarah Londrigan, Gregory Moseley, Natalie Prow, Grant Hansman, Robert Edwards, Chantelle Ahlenstiel, Allison Abendroth, David Tscharke, Jody Hobson-Peters, Robson Kriiger-Loterio, Rhys Parry, Glenn Marsh, Emma Harding, David A. Jacques, Matthew J. Gartner, Wen Shi Lee, Julie McAuley, Paola Vaz, Frank Sainsbury, Michelle D. Tate, Jane Sinclair, Allison Imrie, Stephen Rawlinson, Andrew Harman, Jillian M. Carr, Ebony A. Monson, Merilyn Hibma, Timothy J. Mahony, Thomas Tu, Robert J. Center, Lok Bahadur Shrestha, Robyn Hall, Morgyn Warner, Vernon Ward, Danielle E. Anderson, Nicholas S. Eyre, Natalie E. Netzler, Alison J. Peel, Peter Revill, Michael Beard, Alistair R. Legione, Alexandra J. Spencer, Adi Idris, Jade Forwood, Subir Sarker, Damian F. J. Purcell, Nathan Bartlett, Joshua M. Deerain, Bruce J. Brew, Sassan Asgari, Helen Farrell, Alexander Khromykh, Daniel Enosi Tuipulotu, David Anderson, Sevim Mese, Yaman Tayyar, Kathryn Edenborough, Jasim Muhammad Uddin, Abrar Hussain, Connor J. I. Daymond, Jacinta Agius, Karyn N. Johnson, Paniz Shirmast, Mahdi Abedinzadeshahri, Robin MacDiarmid, Caroline L. Ashley, Jay Laws, Lucy L. Furfaro, Thomas D. Burton, Stephen M. R. Johnson, Zahra Telikani, Mary Petrone, Justin A. Roby, Carolyn Samer, Andreas Suhrbier, April Van Der Kamp, Anthony Cunningham, Celeste Donato, Jackie Mahar, Wesley D. Black, Subhash Vasudevan, Roman Lenchine, Kirsten Spann, Daniel J. Rawle, Penny Rudd, Jessica Neil, Richard Kingston, Timothy P. Newsome, Ki Wook Kim, Johnson Mak, Kym Lowry, Nathan Bryant, Joanne Meers, Jason A. Roberts, Nigel McMillan, Larisa I. Labzin, Andrii Slonchak, Leon E. Hugo, Bennett Henzeler, Natalee D. Newton, Cassandra T. David, Patrick C. Reading, Camille Esneau, Tatiana Briody, Najla Nasr, Donna McNeale, Brian McSharry, Omid Fakhri, Bethany A. Horsburgh, Grant Logan, Paul Howley, Paul Young
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/d6c7d0d84f3d4d78be8859af3bbe8cc3
Autor:
Shouya Feng, Daniel Enosi Tuipulotu, Abhimanu Pandey, Weidong Jing, Cheng Shen, Chinh Ngo, Melkamu B. Tessema, Fei-Ju Li, Daniel Fox, Anukriti Mathur, Anyang Zhao, Runli Wang, Klaus Pfeffer, Daniel Degrandi, Masahiro Yamamoto, Patrick C. Reading, Gaetan Burgio, Si Ming Man
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Guanylate-binding proteins (GBP) have a function in inflammasome formation and pathogen defence. Here the authors show that these GBP proteins are able to kill certain bacteria and promote selective inflammasome activation and that this is mediated b
Externí odkaz:
https://doaj.org/article/ea8e4a282bec420d92c49592fcff8122
Autor:
Michael R Ardern-Jones, Hang T T Phan, Florina Borca, Matt Stammers, James Batchelor, Isabel C Reading, Sophie V Fletcher, Trevor Smith, Andrew S Duncombe
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280079 (2023)
BackgroundThe success of early dexamethasone therapy for hospitalised COVID-19 cases in treatment of Sars-CoV-2 infection may predominantly reflect its anti-inflammatory action against a hyperinflammation (HI) response. It is likely that there is sub
Externí odkaz:
https://doaj.org/article/c401526cf62b4996814b4e6ed5dc1641
Autor:
Jake S. O’Donnell, Ariel Isaacs, Virginie Jakob, Celia Lebas, James B. Barnes, Patrick C. Reading, Paul R. Young, Daniel Watterson, Patrice M. Dubois, Nicolas Collin, Keith J. Chappell
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Various chemical adjuvants are available to augment immune responses to non-replicative, subunit vaccines. Optimized adjuvant selection can ensure that vaccine-induced immune responses protect against the diversity of pathogen-associated infection ro
Externí odkaz:
https://doaj.org/article/261bbf58351944f0a8ef85c9bedab38d
Autor:
Lance R. Nigos, Nichollas E. Scott, Andrew G. Brooks, Malika Ait-Goughoulte, Sarah L. Londrigan, Patrick. C. Reading, Rubaiyea Farrukee
Publikováno v:
Pathogens, Vol 12, Iss 6, p 852 (2023)
Host cell restriction factors are intracellular proteins that can inhibit virus replication. Characterisation of novel host cell restriction factors can provide potential targets for host-directed therapies. In this study, we aimed to assess a member
Externí odkaz:
https://doaj.org/article/4b978ea391eb4398bcf315195a894686