Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C R Wobbe"'
Publikováno v:
Journal of Biological Chemistry. 267:20943-20952
In the gal-his3 hybrid promoter, his3-GG1, GCN4 stimulates transcription at the position normally occupied by a TATA element. This expression requires two elements within gal1-10 sequences, a REB1-binding site and a second element, Z, which resides 2
Autor:
Kevin Struhl, Stephen C. Harrison, C R Wobbe, Michael A. Weiss, Jeng-Shin Lee, Thomas E. Ellenberger
Publikováno v:
Nature. 347:575-578
Protein-DNA recognition is often mediated by a small domain containing a recognizable structural motif, such as the helix-turn-helix or the zinc-finger. These motifs are compact structures that dock against the DNA double helix. Another DNA recogniti
Autor:
C R Wobbe, D R Averett, C M Thompson, C E Donnelly, J B Moore, J M Healy, J D Bradley, E T Buurman
Publikováno v:
Pharmacogenomics. 2(2)
The attempt to develop novel antibiotics, active against organisms resistant to current therapies, has led researchers to seek and explore new drug targets. The rapid sequencing and analysis of entire microbial genomes has identified large numbers of
To investigate the process of TATA box recognition by the TATA box-binding protein (TBP), we have performed a detailed genetic and biochemical analysis of two Saccharomyces cerevisiae TBP mutants with altered DNA-binding specificity. The mutant prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2791292cbe6412ffe6f221204052ec
https://europepmc.org/articles/PMC358739/
https://europepmc.org/articles/PMC358739/
Publikováno v:
The Journal of biological chemistry. 267(29)
In the gal-his3 hybrid promoter, his3-GG1, GCN4 stimulates transcription at the position normally occupied by a TATA element. This expression requires two elements within gal1-10 sequences, a REB1-binding site and a second element, Z, which resides 2
Publikováno v:
Genesdevelopment. 4(4)
We created a library of DNA molecules in which the required TATA element of a yeast gal-his3 promoter is replaced by random-sequence oligomers averaging 16 bp in length. Surprisingly, 1% of such random sequences functionally replace the native yeast
Publikováno v:
Philosophical Transactions of the Royal Society of London. B, Biological Sciences. 317:439-453
The replication of DNA containing either the polyoma or SV40 origin has been done in vitro . Each system requires its cognate large-tumour antigen (T antigen) and extracts from cells that support its replication in vivo . The host-cell source of DNA
Publikováno v:
Biochemistry. 23:6565-6569
The structure of empty capsids of Kilham rat virus, an autonomous parvovirus with icosahedral symmetry, was investigated by small-angle neutron scattering. From the forward scatter, the molecular weight was determined to be 4.0 x 10(6), and from the
Autor:
Sankar Mitra, C. R. Wobbe
Publikováno v:
Proceedings of the National Academy of Sciences. 82:8335-8339
Revie et al. [Revie, D., Tseng, B. Y., Grafstrom, R. H. & Goulian, M. (1979) Proc. Natl. Acad. Sci. USA 76, 5539-5543] have proposed that the double-stranded replicative form (RF) DNA of the autonomous rodent parvovirus H-1 has protein of 60 kDa cova
Extracts (0.2 M NaCl) of HeLa cells support replication of DNA containing simian virus 40 (SV40) origin in the presence of SV40 large tumor (T) antigen. The reaction leads to the accumulation of high molecular weight products that represent DNA conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d790d0e88eadf78ab5a659159c5356d
https://europepmc.org/articles/PMC390621/
https://europepmc.org/articles/PMC390621/