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pro vyhledávání: '"C R Van der Sand"'
Autor:
Maria Elvira Wagner Ferreira, Marilu Fiegenbaum, L C Van der Sand, Renan Canibal Pires, C R Van der Sand, Silvana Almeida, Lisiane Smiderle, Mara H. Hutz
Publikováno v:
Europe PubMed Central
Lipid-lowering therapy has shown a high degree of variability in clinical response and there is evidence that the variability in drug response between individuals is due to genetic factors. Thirteen single nucleotide polymorphisms (SNPs) within the E
Autor:
Renan Canibal Pires, Maria Elvira Wagner Ferreira, Fabiano Roldao Silveira, Mara H. Hutz, L C Van der Sand, Marilu Fiegenbaum, C R Van der Sand
Publikováno v:
The Pharmacogenomics Journal. 5:359-364
We investigated the effect of single-nucleotide polymorphisms in sterol regulatory element-binding factors-1a and -2 (SREBF-1a and SREBF-2) and SREBF cleavage-activating protein (SCAP) genes on lipid-lowering response to simvastatin. In all, 146 hype