Zobrazeno 1 - 10
of 30
pro vyhledávání: '"C R Stevens"'
Autor:
R Klocke, Paul I. Mapp, Patrick J. Gallagher, C R Stevens, David R. Blake, David A. Walsh, Jasvinder K. Chana
Publikováno v:
Arthritis & Rheumatism. 44:1534-1539
Objective. To determine the localization of 3-nitrotyrosine (3-NT), a footprint marker of peroxynitrite (ONOO-) and other reactive nitrogen species, to the inflamed human synovium and to compare this with normal synovial and nonsynovial tissue of hum
Autor:
John A. Howell, M. Smith, Julian B. Chaudhuri, Tulin Bodamyali, C R Stevens, P. McFetridge, Michael Horrocks
Publikováno v:
Food and Bioproducts Processing. 78:19-24
Porcine-derived dermal collagen has been studied as a potential scaffold for the production of tissue engineered products. The surface structure of the collagen has been examined by low temperature-scanning electron microscopy and reveals an open fib
Publikováno v:
Annals of the Rheumatic Diseases. 58:573-581
OBJECTIVE—To investigate endothelial cell adhesion molecule expression and leucocyte adhesion to endothelial cells isolated from the microvasculature of rheumatoid arthritic synovial tissue (SMEC) in comparison with similar cells isolated from heal
Publikováno v:
The Chemical Educator. 4:12-15
A laboratory exercise that introduces differential scanning calorimetry (DSC) is presented. In order to connect this basic physical chemistry technique with an application in the biological sciences, students investigated the thermodynamic properties
Publikováno v:
Annals of the Rheumatic Diseases. 57:703-710
Hypothesis Persistent synovitis results from a hypoxia driven progressive transition to glycolytic metabolism that promotes transcriptional changes permissive to unresolved inflammation as the disease progresses. Erosion of cartilage and bone may inv
Autor:
Zhiying Zhang, Janos M. Kanczler, Paul G. Winyard, T. Sahinoglu, Timothy M. Millar, Graham Ellis, D R Blake, C R Stevens, Richard A. Harrison, Shahid Jawed, Mustapha Benboubetra, S. E. Edmonds, Karl Gaffney
Publikováno v:
ResearcherID
Europe PubMed Central
Europe PubMed Central
Publikováno v:
Scandinavian Journal of Rheumatology. 24:21-26
Publikováno v:
Scandinavian Journal of Rheumatology. 24:131-136
Antioxidant depletion in a normal adult increases the risk of developing rheumatoid arthritis (1). We discuss how redox processes "control" the inflammatory reaction and suggest that the synovium is a peculiarly "redox-sensitive" microenvironment. Th
Publikováno v:
Annals of the Rheumatic Diseases. 51:1117-1122
Experimental evidence suggests that rheumatoid synovitis may be perpetuated by the generation of reactive oxygen species during hypoxic reperfusion injury. The latter occurs because increased intra-articular pressure during exercise exceeds synovial
Publikováno v:
Arthritis & Rheumatism. 35:401-406
Objective. In vitro studies investigating the role of the synovial endothelium in the pathogenesis of rheumatoid arthritis (RA) have, until recently, been performed using cultured endothelial cells of nonsynovial macrovascular origin. In an attempt t