Zobrazeno 1 - 10
of 51
pro vyhledávání: '"C R Manclark"'
Publikováno v:
Infection and Immunity. 58:4045-4048
The ability of heat-labile toxin (HLT) from Bordetella parapertussis to induce skin lesions in guinea pigs was found to be inhibited by lipids isolated from skin layers of adult mice, which are refractory to the lesion-inducing activity of HLT. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea91539bebaf0f6a8c1e56709bf2164f
https://doi.org/10.1128/iai.58.12.4045-4048.1990
https://doi.org/10.1128/iai.58.12.4045-4048.1990
Publikováno v:
The Journal of Immunology. 144:3529-3534
To understand the immunologic characteristics of pertussis toxin molecule and to explore the possibility of developing a synthetic vaccine, T cell epitopes on the enzymatic S1 subunit of pertussis toxin were studied by measuring the proliferative res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1d7bfe2f6e948c65c610f461161a9d
https://doi.org/10.4049/jimmunol.144.9.3529
https://doi.org/10.4049/jimmunol.144.9.3529
Publikováno v:
Biotechnology (Reading, Mass.). 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::daca8b4cb7c17c653253c72b8af4cc8e
https://pubmed.ncbi.nlm.nih.gov/1600382
https://pubmed.ncbi.nlm.nih.gov/1600382
Immunization with the B oligomer of pertussis toxin protected neonatal mice from a lethal respiratory challenge with Bordetella pertussis. All mice immunized with 8 micrograms of B oligomer survived aerosol challenge and had peripheral leukocyte coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47835f2acb478c2d65d4151e33f31a3a
https://europepmc.org/articles/PMC313777/
https://europepmc.org/articles/PMC313777/
Injection of sonic extracts of Bordetella parapertussis into the shaved backs of guinea pigs produced hemorrhagic necrosis, which previously has been attributed to the action of heat-labile toxin. As heat-labile toxin was purified from this crude mix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c47df4aff6e3cea49c68cbbdc774f3e
https://europepmc.org/articles/PMC258647/
https://europepmc.org/articles/PMC258647/
Publikováno v:
FEMS microbiology letters. 55(3)
A purification scheme was devised for a 69-kDa outer membrane protein of Bordetella pertussis, a virulence-associated protein which may play a role in the pathogenesis of the organism. The protein was purified to apparent homogeneity by heating B. pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b21ecc92174fe154994a21b889b1769
https://pubmed.ncbi.nlm.nih.gov/2323550
https://pubmed.ncbi.nlm.nih.gov/2323550
Publikováno v:
Advances in Mucosal Immunology ISBN: 9789401073233
Pertussis (whooping cough) is a disease of the respiratory tract that may be characterized by episodes of paroxysmal coughing and can be fatal in children younger than one year of age. Filamentous hemagglutinin (FHA) is a 200 kDa protein thought to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8faee109394357c22c6f5a2b6e40252
https://doi.org/10.1007/978-94-009-1848-1_259
https://doi.org/10.1007/978-94-009-1848-1_259
Autor:
D L Burns, C R Manclark
Publikováno v:
Journal of Biological Chemistry. 261:4324-4327
Pertussis toxin is composed of an enzymatically active A subunit and a binding component (B oligomer). Both the holotoxin and the isolated A subunit have previously been shown to exhibit NAD glycohydrolase activity although the A subunit is more acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a52179690e049f2f9c4d9ff89e20368
https://doi.org/10.1016/s0021-9258(17)35664-8
https://doi.org/10.1016/s0021-9258(17)35664-8
Publikováno v:
Infection and Immunity. 31:1223-1231
Gamma globulins were obtained from rabbits hyperimmunized with the filamentous hemagglutinin (FHA) or the leukocytosis-promoting factor hemagglutinin (LPF.HA) of Bordetella pertussis. Double immunodiffusion analyses showed the antibodies to be highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228ea77cbe90a80f064b1389c1b7715e
https://doi.org/10.1128/iai.31.3.1223-1231.1981
https://doi.org/10.1128/iai.31.3.1223-1231.1981
Publikováno v:
Infection and Immunity. 45:718-725
Lymphocytosis promoting factor (LPF) of Bordetella pertussis is a protein toxin which may have a role in the pathogenesis of pertussis. Since macrophages have an important role in the control of respiratory infections, the in vitro effects of LPF on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03e95de2af2a7afe162e0261a2f0d83
https://doi.org/10.1128/iai.45.3.718-725.1984
https://doi.org/10.1128/iai.45.3.718-725.1984