Zobrazeno 1 - 10
of 178
pro vyhledávání: '"C R Manclark"'
Autor:
R. Parton
Publikováno v:
Journal of Medical Microbiology. 23:93-93
Publikováno v:
Infection and Immunity. 58:4045-4048
The ability of heat-labile toxin (HLT) from Bordetella parapertussis to induce skin lesions in guinea pigs was found to be inhibited by lipids isolated from skin layers of adult mice, which are refractory to the lesion-inducing activity of HLT. These
Publikováno v:
The Journal of Immunology. 144:3529-3534
To understand the immunologic characteristics of pertussis toxin molecule and to explore the possibility of developing a synthetic vaccine, T cell epitopes on the enzymatic S1 subunit of pertussis toxin were studied by measuring the proliferative res
Publikováno v:
Biotechnology (Reading, Mass.). 20
Immunization with the B oligomer of pertussis toxin protected neonatal mice from a lethal respiratory challenge with Bordetella pertussis. All mice immunized with 8 micrograms of B oligomer survived aerosol challenge and had peripheral leukocyte coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47835f2acb478c2d65d4151e33f31a3a
https://europepmc.org/articles/PMC313777/
https://europepmc.org/articles/PMC313777/
Injection of sonic extracts of Bordetella parapertussis into the shaved backs of guinea pigs produced hemorrhagic necrosis, which previously has been attributed to the action of heat-labile toxin. As heat-labile toxin was purified from this crude mix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c47df4aff6e3cea49c68cbbdc774f3e
https://europepmc.org/articles/PMC258647/
https://europepmc.org/articles/PMC258647/
Publikováno v:
FEMS microbiology letters. 55(3)
A purification scheme was devised for a 69-kDa outer membrane protein of Bordetella pertussis, a virulence-associated protein which may play a role in the pathogenesis of the organism. The protein was purified to apparent homogeneity by heating B. pe
Publikováno v:
Advances in Mucosal Immunology ISBN: 9789401073233
Pertussis (whooping cough) is a disease of the respiratory tract that may be characterized by episodes of paroxysmal coughing and can be fatal in children younger than one year of age. Filamentous hemagglutinin (FHA) is a 200 kDa protein thought to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8faee109394357c22c6f5a2b6e40252
https://doi.org/10.1007/978-94-009-1848-1_259
https://doi.org/10.1007/978-94-009-1848-1_259
Autor:
D L Burns, C R Manclark
Publikováno v:
Journal of Biological Chemistry. 261:4324-4327
Pertussis toxin is composed of an enzymatically active A subunit and a binding component (B oligomer). Both the holotoxin and the isolated A subunit have previously been shown to exhibit NAD glycohydrolase activity although the A subunit is more acti
Publikováno v:
Infection and Immunity. 31:1223-1231
Gamma globulins were obtained from rabbits hyperimmunized with the filamentous hemagglutinin (FHA) or the leukocytosis-promoting factor hemagglutinin (LPF.HA) of Bordetella pertussis. Double immunodiffusion analyses showed the antibodies to be highly