Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C R DeBold"'
Autor:
David N. Orth, Richard V. Jackson, D Gaitan, C R DeBold, William R. Sheldon, Wendell E. Nicholson, G S DeCherney, G Dickstein
Publikováno v:
The Journal of clinical endocrinology and metabolism. 81(8)
The CRH test may sometimes be useful in the differential diagnosis of Cushing's syndrome, because most patients with pituitary ACTH-dependent Cushing's syndrome (Cushing's disease) respond to CRH, but those with other causes of Cushing's syndrome usu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13d7be8eae3afadd1966be7d5674117
https://pubmed.ncbi.nlm.nih.gov/8768855
https://pubmed.ncbi.nlm.nih.gov/8768855
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 9(9)
ACTH secretion by tumors of nonpituitary origin is characteristically resistant to negative feedback regulation by glucocorticoids. One possible mechanism for the phenomenon could be a structural defect in the intracellular glucocorticoid receptor (G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebeb3b75b7c3385303407c0606f839a
https://pubmed.ncbi.nlm.nih.gov/7491111
https://pubmed.ncbi.nlm.nih.gov/7491111
Publikováno v:
Pharmacopsychiatry. 25(4)
We evaluated 20 patients with Cushing's disease (i.e., Cushing's syndrome due to ACTH-secreting pituitary microadenoma) and 20 patients with Major Depressive Disorder (MDD) using the Structured Clinical Interview for DSM-III-R (SCID) and Research Dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cf3b04cae4cc435a536347cc5d043f
https://pubmed.ncbi.nlm.nih.gov/1528959
https://pubmed.ncbi.nlm.nih.gov/1528959
Publikováno v:
Endocrinology. 130(4)
Cells of the immune system can produce and respond to peptide hormones associated with the endocrine system. However, the physiological significance of these endocrine-immune interactions is not known. It has been postulated that cells of the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91ea41e9e2c9ce51375d38cd20f087d
https://pubmed.ncbi.nlm.nih.gov/1312443
https://pubmed.ncbi.nlm.nih.gov/1312443
Publikováno v:
The Journal of reproductive medicine. 35(3)
Hyperandrogenic states in women may alter hypothalamic pituitary response. The pituitary function of a 64-year-old postmenopausal woman with a testosterone-secreting (T-secreting) ovarian neoplasm was assessed with a combined infusion of ovine cortic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f84df11bef1238fc8b953c1fc76b95d9
https://pubmed.ncbi.nlm.nih.gov/2182850
https://pubmed.ncbi.nlm.nih.gov/2182850
Autor:
C R DeBold, A N Alexander, Jean Rivier, Donald P. Island, G S DeCherney, Wylie Vale, Catherine Rivier, David N. Orth, Richard V. Jackson, J Spiess
Publikováno v:
Journal of Clinical Investigation. 71:587-595
Synthetic ovine corticotropin-releasing factor (CRF) was administered to normal male volunteer subjects as an intravenous bolus or 30-s infusion. Doses of CRF ranging from 0.001 to 30 micrograms/kg body wt were administered, and plasma immunoreactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1b3b64680be0625e887eab320af01f
https://doi.org/10.1172/jci110804
https://doi.org/10.1172/jci110804
Autor:
Jean Rivier, A N Alexander, Richard V. Jackson, William R. Sheldon, G S DeCherney, Wylie Vale, C R DeBold, David N. Orth
Publikováno v:
Journal of Clinical Investigation. 73:533-538
Arginine vasopressin (AVP) stimulates ACTH release in man and acts synergistically with synthetic ovine corticotropin-releasing factor (oCRF) in vitro. This study was designed to examine in man the combined effects of synthetic AVP (10 U intramuscula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bc040eb55e684d280dfc6a0cf57516
https://doi.org/10.1172/jci111240
https://doi.org/10.1172/jci111240
Autor:
Donald P. Island, Spyros N. Pavlou, Jean Rivier, Wylie Vale, Gail Wakefield, C R DeBold, David Rabin
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 63:303-308
The ability of single doses of a LHRH antagonist [Ac-delta 3Pro1, 4F-D-Phe2, D-Trp3,6]LHRH (4F-antagonist) to suppress serum gonadotropin and testosterone levels was studied in six normal men. The 4F-antagonist was given sc at four doses: 40, 80, 160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8d50d5f7061f1b827fd7bb2b00cf16
https://doi.org/10.1210/jcem-63-2-303
https://doi.org/10.1210/jcem-63-2-303
Autor:
Wylie Vale, Jean Rivier, Richard V. Jackson, Joachim Spiess, Catherine Rivier, C R DeBold, A N Alexander, G S DeCherney, David N. Orth
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 55:1017-1019
Corticotropin-releasing factor (CRF) was administered as an iv bolus to two young women with mild Cushing's disease shortly before and one week after successful transsphenoidal microadenomectomy. The dose of CRF (1 microgram/kg body weight) had previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e104d2f67f99099bf0c7c0e820b5f86
https://doi.org/10.1210/jcem-55-5-1017
https://doi.org/10.1210/jcem-55-5-1017
Publikováno v:
Biochemical and biophysical research communications. 155(2)
The proopiomelanocortin (POMC) gene is expressed in many normal nonpituitary tissues, in addition to the pituitary. POMC-derived peptides have also been detected in many pheochromocytomas. We examined poly(A)+ RNA from 5 pheochromocytomas with a POMC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40dc2688e8562a362db3463f4c96f77e
https://pubmed.ncbi.nlm.nih.gov/2844181
https://pubmed.ncbi.nlm.nih.gov/2844181