Zobrazeno 1 - 10
of 31
pro vyhledávání: '"C R, Noe"'
Autor:
C R, Noe, M, Noe-Letschnig
Publikováno v:
Die Pharmazie. 76(8)
Angiotensin-2 converting enzyme (ACE2), a key element of the renin-angiotensin-system (RAS), is not only the direct target of infection by the human SARS-Cov-2 virus but is at the same the root for the complex pathogenetic events of COVID-19. From a
Autor:
C R, Noe, P, Handschuh, L, Wolfslehner, C A, Noe, M, Noe-Letschnig, D, Soucek-Noe, R, Lanzenberger
Publikováno v:
Die Pharmazie. 75(10)
Type 2 diabetes mellitus is characterized by insulin resistance and elevated blood glucose levels. Treatment protocols generally include dietary restriction of sugar, as well as drugs aiming at a reduction of blood glucose, mainly by activating the i
Publikováno v:
Die Pharmazie. 70(8)
Medicinal products obtained by recombinant DNA technology are complex molecules and demonstrate a high degree of molecular heterogeneity. Charge heterogeneity and isoform pattern of this class of medicines, are parameters important for their quality,
Autor:
B, Lachmann, C R, Noe
Publikováno v:
Die Pharmazie. 68(7)
Acarbose (Glucobay, Bayer AG) acts as a potent alpha-glucosidase-inhibitor, which delays the intestinal starch digestion resulting in a reduction of postprandial blood glucose and insulin levels. Acarbose is a pseudo-tetrasaccharide, with two D-gluco
Publikováno v:
Die Pharmazie. 68(2)
In this paper we propose the use of lactic acid oligomers (OLAs) as prodrug moieties. Two synthetic approaches are presented, on the one hand a non selective oligomerisation of lactic acid and on the other hand a block synthesis to tetramers of lacti
Publikováno v:
Molecular and General Genetics MGG. 251:499-502
A 711-bp cDNA encoding a cysteine proteinase inhibitor (cystatin) was isolated from a cDNA library prepared from 7-10 cm Sorghum bicolor seedlings. The nearly full-length cDNA clone encodes 130 amino acid residues, which include the Gin-Val-Val-Ala-G
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 55:1304-1306
The title compound, C 17 H 16 N 4 O 2 , was synthesized by the reaction of 4,6-dichloro-1,3,5-triazin-2-ylamine, obtained from cyanuric chloride, with powdered sodium hydroxide in benzyl alcohol. It crystallizes as a centrosymmetric hydrogen-bonded d
Publikováno v:
Die Pharmazie. 62(6)
A simple, rapid and specific ion-pair HPLC method for the determination of (R,R)-glycopyrronium bromide and its related impurities is presented, and parameters affecting the chromatographic properties of these compounds are discussed. Optimal analyte
Autor:
C. R. Noe, B. Lachmann
Publikováno v:
Scientia Pharmaceutica
Volume 69
Issue 4
Pages 299-314
Pages 596-611
Volume 69
Issue 4
Pages 299-314
Pages 596-611
Capillary electrophoresis is a versatile analytical technique for the determination of a very widespread range of compounds. Many applications for the separation of different pharmaceuticals, ions, herbicides and biomolecules such as DNA, proteins an
[Synthesis and pharmacodynamic activity of 2-(3-(2-phenylethyl)benzofuran-2-yl)-N-propyl-ethanamine]
Publikováno v:
Archiv der Pharmazie. 328(4)
The benzofuranethanamines 3a and 3b were synthesized and pharmacologically tested to investigate structure-activity relationships with antiarrhythmic compounds. The key-step in the synthesis was the chemoselective reduction of the chloroacetyl-dihydr