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pro vyhledávání: '"C R, McCurdy"'
Autor:
Alvin V. Terry, C. R. McCurdy, Ritchie Williamson, James R. Pauly, Mahanandeeshwar Gattu, J. W. Beach, J. A. Sparks
Publikováno v:
Neuropharmacology. 37:93-102
In the present study, lobeline and two structurally simplified analogs were evaluated for activity in muscarinic and nicotinic binding assays, a functional assay for nicotinic receptor activation (86Rb+ efflux from striatal synaptosomes) and an acety
Publikováno v:
Organic letters. 2(6)
[formula: see text] The phenolic hydroxy group of opiate-derived ligands is of known importance for biological activity. On the basis of its putative role as a hydrogen-bonding donor in the interaction with opioid receptors, it was replaced with a su
Publikováno v:
Electrophoresis. 20(1)
High performance capillary electrophoresis (HPCE) methods are described that will separate the enantiomers of various lobeline analogs synthesized in these laboratories. "Cyclodextrin array analysis" was used for preliminary screening and electrophor