Zobrazeno 1 - 10
of 43
pro vyhledávání: '"C R, Lyons"'
Publikováno v:
Journal of Leukocyte Biology. 69:538-547
The pathobiology of allergic asthma is being studied using murine models, most of which use systemic priming followed by pulmonary challenges with the immunizing antigen. In general, mice develop eosinophilic pulmonary inflammation, increased antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fe225c927c4f44b8763bb2eb570b3e
https://doi.org/10.1189/jlb.69.4.538
https://doi.org/10.1189/jlb.69.4.538
Publikováno v:
Immunology. 91:167-175
Atopic asthmatics, compared to non-atopic individuals, exhibit an increased amount of serum antigen-specific IgE and IgG4 antibody directed toward many aeroallergens. We tested the hypothesis that this difference between atopics and non-atopics exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d063a85b956ed6a62c26a0ad181e963e
https://doi.org/10.1046/j.1365-2567.1997.00234.x
https://doi.org/10.1046/j.1365-2567.1997.00234.x
Publikováno v:
The Journal of Immunology. 158:1772-1778
Mice infected intratracheally with Cryptococcus neoformans (Cne) require CD4 and CD8 T cells, IFN-gamma, and M phi production of nitric oxide (NO) for effective resolution of the pulmonary infection. Differences exist among strains of mice in clearin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c9fb3fae2f5507b09d5e1f75c29613
https://doi.org/10.4049/jimmunol.158.4.1772
https://doi.org/10.4049/jimmunol.158.4.1772
Autor:
Frederick Koster, Edward B. Barr, Steven Park, Robert Sherwood, David S. Perlin, Leslie Myers, Andrew P. Gigliotti, C. R. Lyons, Trevor Brasel, Robert C. Layton
Vaccines against primary pneumonic plague, a potential bioweapon, must be tested for efficacy in well-characterized nonhuman primate models. Telemetered cynomolgus macaques ( Macaca fascicularis ) were challenged by the aerosol route with doses equiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607bc112e601956b2e06eea680760c7e
https://europepmc.org/articles/PMC2897392/
https://europepmc.org/articles/PMC2897392/
Publikováno v:
Journal of Biological Chemistry. 267:6370-6374
Macrophages activated by exposure to cytokines and/or to endotoxin produce nitric oxide (NO.), a free radical that is a mediator of the host response to infection. Activation induces the expression of nitric oxide synthase, the enzyme that catalyzes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83ddb31b2cf33ead217002c0fe305cf
https://doi.org/10.1016/s0021-9258(18)42704-4
https://doi.org/10.1016/s0021-9258(18)42704-4
Publikováno v:
Photochemistry and photobiology. 74(1)
We have developed a model of cutaneous herpes simplex virus-1 (HSV-1) reactivation in SKH-1 hairless mice which closely mimics the condition in humans. Sixty plaque-forming units of HSV-1 strain 17 syn+ were applied to a superficially abraded area on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88b5677f7bdba3dfda4db3ee49698940
https://pubmed.ncbi.nlm.nih.gov/11460531
https://pubmed.ncbi.nlm.nih.gov/11460531
Ig heavy chain complex-linked genes influence the immune response in a murine cryptococcal infection
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(7)
A murine pulmonary infection with Cryptococcus neoformans (Cne) has been used to determine mechanisms regulating effective T cell-mediated immunity in the lungs. In BALB/c and C.B-17 mice, following intratracheal deposition of Cne, the fungus initial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6471513e7cd111c5729fe278a0d81e14
https://pubmed.ncbi.nlm.nih.gov/10490991
https://pubmed.ncbi.nlm.nih.gov/10490991
Publikováno v:
American journal of respiratory cell and molecular biology. 20(6)
Nonspecific airway hyperresponsiveness (AHR) is a hallmark of human asthma. Both airway eosinophilia and high serum levels of total and antigen-specific immunoglobulin E (IgE) are associated with AHR. It is unclear, however, whether either eosinophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662d1ac454170a12a99398f26f77b39d
https://pubmed.ncbi.nlm.nih.gov/10340953
https://pubmed.ncbi.nlm.nih.gov/10340953
Publikováno v:
Handbook of Animal Models of Infection ISBN: 9780127753904
Publisher Summary This chapter presents various methods that use the respiratory route of infection to produce a cryptococcal pneumonia in mice. The advantages of using mice model include lower cost and availability of various genetically characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aad0774f0682560c242715d13f2ede2e
https://doi.org/10.1016/b978-012775390-4/50221-9
https://doi.org/10.1016/b978-012775390-4/50221-9
Publikováno v:
American journal of respiratory cell and molecular biology. 13(1)
Increasing evidence indicates that T cell-dependent, interferon gamma (IFN gamma)-induced activation of murine macrophages and nitric oxide (NO) production plays an important role in host defenses against many microorganisms. A role for this mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c67eb14e3f915d3cd2898397719d246
https://pubmed.ncbi.nlm.nih.gov/7598935
https://pubmed.ncbi.nlm.nih.gov/7598935