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pro vyhledávání: '"C R, Goodlett"'
Autor:
C R, Goodlett, K H, Horn
Publikováno v:
Alcohol Research & Health
Numerous mechanisms likely contribute to the damaging effects of prenatal alcohol exposure on the developing fetus and particularly the developing central nervous system (CNS). The coexistence of a multitude of mechanisms that may act simultaneously
Autor:
E P, Riley, J D, Thomas, C R, Goodlett, A Y, Klintsova, W T, Greenough, B L, Hungund, F, Zhou, Y, Sari, T, Powrozek, T K, Li
Publikováno v:
Alcoholism, clinical and experimental research. 25(5 Suppl)
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chair was Edward P. Riley. The presentations were (1) Does alcohol withdrawal contribute to fetal alcohol effects? by Jennifer D. Thomas and Edwa
Publikováno v:
Alcoholism, clinical and experimental research. 24(4)
Eyeblink classical conditioning is a learning task that engages well-defined neural circuitry in the cerebellum and brainstem. Binge-like exposure to alcohol during the neonatal brain growth spurt in rats produces neurotoxic effects on both the cereb
Publikováno v:
Brain research. 800(1)
The effects of complex motor task learning on subsequent motor performance of adult rats exposed to alcohol on postnatal days 4 through 9 were studied. Male and female Long-Evans rats were assigned to one of three treatments: (1) alcohol exposure (AE
Autor:
M E, Stanton, C R, Goodlett
Publikováno v:
Alcoholism, clinical and experimental research. 22(1)
Eyeblink conditioning depends on an identified brainstem-cerebellar circuit and may be useful in functional studies of early cerebellar damage produced by neurotoxicants. The present study asked whether binge-like neonatal ethanol exposure that damag
Publikováno v:
Alcoholism, clinical and experimental research. 21(7)
Because therapeutic approaches to fetal alcohol effects in humans have been rare, this study explored the rehabilitative effect of complex motor training on an animal model of binge drinking in the third trimester of human pregnancy. Neonatal alcohol
Autor:
C R, Goodlett, A T, Eilers
Publikováno v:
Alcoholism, clinical and experimental research. 21(4)
Previous research has shown that the early neonatal period of rats is one of enhanced vulnerability to cerebellar Purkinje cell loss associated with binge-like alcohol exposure, with a prominent sensitive period during the first neonatal week. In thi
Publikováno v:
Developmental psychobiology. 29(5)
The importance of the timing and number of episodes of bingelike alcohol exposure in neonatal rats on subsequent behavioral outcomes was evaluated with a parallel bar task and a spatial conditional alternation task. Different groups of Sprague-Dawley
Publikováno v:
Neurotoxicology. 10(3)
Genetic factors have been implicated as contributing to the considerable variation in the severity of alcohol-related birth defects in offspring of women who drink heavily during pregnancy. Two animal models of alcohol-related developmental effects i
Publikováno v:
Behavioral neuroscience. 97(6)
Response perseveration following septal lesions, demonstrated on tasks that require change of a learned pattern of responding, depends in part on a relatively constant motivational context. The present experiment examined the effects of concurrent ch