Výsledky vyhledávání - "C R, Drogemuller"

Mediation of cytotoxic immune responses against human tumor-associated antigens by xenogeneic immune RNA

Autor: D H, Kern, D, Fritze, C R, Drogemuller, Y H, Pilch

Publikováno v: Journal of the National Cancer Institute. 57(1)

Xenogeneic immune RNA (I-RNA), extracted from the lymphoid organs of sheep or guinea pigs immunized with human tumor cells, mediated in vitro cytotoxic immune responses that were directed specifically against tumor-associated antigens of human tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5e15a7cabf3ddde2ab0e90dd8839c3e
https://pubmed.ncbi.nlm.nih.gov/1003510

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Production of antisera with specificity for malignant melanoma and human fetal skin

Autor: D, Fritze, D H, Kern, C R, Drogemuller, Y H, Pilch

Publikováno v: Cancer research. 36(2 Pt 1)

Complement-dependent cytotoxic antibodies to common cell surface antigens of cultured melanoma cells were produced in guinea pigs. At appropriate dilution, melanoma antisera were cytotoxic only to melanoma target cells. Following absorption with pool

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8985ee7dd0f062d4f3e2779c7505c8b
https://pubmed.ncbi.nlm.nih.gov/56991

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Immune cytolysis of rat tumor cells mediated by syngeneic 'immune' RNA

Autor: D H, Kern, C R, Drogemuller, Y H, Pilch

Publikováno v: Journal of the National Cancer Institute. 52(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::187f1a1e97d07397889f0b5df158641d
https://pubmed.ncbi.nlm.nih.gov/4810971

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Specificity of antitumor immune reactions mediated by xenogeneic immune RNA

Autor: D H, Kern, C R, Drogemuller, N, Chow, D D, Holleman, Y H, Pilch

Publikováno v: Journal of the National Cancer Institute. 58(1)

Evidence that xenogeneic immune RNA (I-RNA) mediated specific cytotoxic immune responses against human tumor-associated antigens was obtained from in vitro studies in two autologous melanoma systems. In these systems, malignant melanoma target cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::714e401b233ef420044d575b17b89742
https://pubmed.ncbi.nlm.nih.gov/833854

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Development of a miniaturized, improved nucleic acid precursor incorporation assay for chemosensitivity testing of human solid tumors

Autor: D H, Kern, C R, Drogemuller, M C, Kennedy, S U, Hildebrand-Zanki, N, Tanigawa, V K, Sondak

Publikováno v: Cancer research. 45(11 Pt 1)

Two technological problems limit the usefulness of chemosensitivity assays: low success rates (generally 30-60%); and the requirement for large numbers of tumor cells (5 X 10(5)/dish). To solve these problems, we developed a miniaturized, improved, n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b21058b378bfef477a74fc32662e4b01
https://pubmed.ncbi.nlm.nih.gov/4053017

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Detection of antibodies bound to tumor cell surface antigens with radioiodinated Staphylococcus aureus protein A (SPA)

Autor: Shankar K. Nayak, C. R. Drogemuller, Yosef H. Pilch, F. B. Knotts

Publikováno v: Cancer Immunology and Immunotherapy. 5

Staphylococcal protein A (SPA) is known to bind to the Fc portion of certain subclasses of IgG. On the basis of this property, radioiodinated SPA (125I-SPA) was used to detect antibodies reacting with surface antigens of tumor cells. Target cells der

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b207a0f9aad339875c3c94372874ea6
https://doi.org/10.1007/bf00200147

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