Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C R, Albrightson"'
Publikováno v:
Journal of the American Society of Nephrology : JASN. 8(6)
Clusterin, a multifunctional protein with complement blocking activity, and fibrin, a product of thrombin9s enzymatic activity, are present in the kidney during acute and chronic renal failure. The role of thrombin in regulating clusterin mRNA in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07296e45959157e431e8e12f414e56d2
https://pubmed.ncbi.nlm.nih.gov/9189857
https://pubmed.ncbi.nlm.nih.gov/9189857
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 44(6)
We assessed the effect of a cytokine inhibitor, compound SKF 86002 (a bicyclic imidazole), on changes in renal hemodynamics (renal blood flow and glomerular filtration rate) that occur acutely following immune injury of glomerular mesangial cells.Inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::068ef35632452962f884dc4004deaba5
https://pubmed.ncbi.nlm.nih.gov/8795301
https://pubmed.ncbi.nlm.nih.gov/8795301
Publikováno v:
Molecular pharmacology. 47(6)
Thrombin-mediated down-regulation of endothelin (ET) receptors was studied in rat glomerular mesangial cells. Overnight incubation of mesangial cells with thrombin (10 nM) resulted in a significant decrease (67%) in the number of ET receptors, with n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efeedf30e5e3572f09f2cd944e2c4e8d
https://pubmed.ncbi.nlm.nih.gov/7603455
https://pubmed.ncbi.nlm.nih.gov/7603455
Autor:
C R, Albrightson, P J, Bugelski, T A, Berkhout, B, Jackson, W D, Kerns, A J, Organ, A M, Badger
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
Azaspiranes are novel immunomodulators which are effective in a variety of autoimmune diseases. One azaspirane analog, SKF 105685 (N,N-dimethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine dihydrochloride), caused a decrease in total serum chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dc8444badb84fb1c32f37cf64076198
https://pubmed.ncbi.nlm.nih.gov/7853183
https://pubmed.ncbi.nlm.nih.gov/7853183
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(1)
The effect of thrombin on mesangial cell function was investigated. Thrombin caused a dose-dependent increase in [3H] thymidine incorporation (EC50 = 0.36 +/- 0.09 U/ml), intracellular calcium [(Ca++)i] mobilization (EC50 = 1.9 +/- 0.5 U/ml) and pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b824da2b8a928095ba0c90074b2ed167
https://pubmed.ncbi.nlm.nih.gov/1403802
https://pubmed.ncbi.nlm.nih.gov/1403802
Publikováno v:
Transplantation proceedings. 23(1 Pt 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73692feda73da4bae22ab286397ac5be
https://pubmed.ncbi.nlm.nih.gov/1990512
https://pubmed.ncbi.nlm.nih.gov/1990512
Autor:
C R, Albrightson-Winslow, B, Brickson, D P, Brooks, W M, Bryan, N, Caldwell, L B, Kinter, M L, Moore, P, Nambi, F L, Stassen, W F, Huffman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(1)
A series of vasopressin analogs with various amino acid tail modifications were tested for antidiuretic agonist and antagonist (water diuretic) activity in the water-loaded indomethacin-treated and hydropenic dogs, respectively. Changing the carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28fa83debf5a637083e5ab8bed793f7f
https://pubmed.ncbi.nlm.nih.gov/1988664
https://pubmed.ncbi.nlm.nih.gov/1988664
Autor:
C R, Albrightson-Winslow, B, Brickson, A, King, D, Olivera, B, Short, C, Saunders, A M, Badger
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 255(1)
MRL/Mp-lpr/lpr (MRL/lpr) mice were studied from 6 to 19 weeks of age. Proteinuria began to increase at 15 weeks, and continued to increase until the animals were sacrificed at 19 weeks. This proteinuria was associated with lymphadenopathy and splenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cba7820d9b06093efc5dfc79557b113
https://pubmed.ncbi.nlm.nih.gov/2145424
https://pubmed.ncbi.nlm.nih.gov/2145424
Publikováno v:
The Journal of Immunology. 135:1872-1877
Incubation of cultured human umbilical vein endothelial cells with factors derived from human peripheral blood mononuclear cells (MNCF) or adherent monocytes (AMF) resulted in concentration-and time-dependent increases in prostacyclin and prostagland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2675856c0951b3b293176a56a62c707
https://doi.org/10.4049/jimmunol.135.3.1872
https://doi.org/10.4049/jimmunol.135.3.1872
Autor:
Kenneth A. Newlander, C R Albrightson-Winslow, Nancy Caldwell, L. B. Kinter, Drake S. Eggleston, Michael L. Moore, G. Dytko, Heidi G. Bryan, Bridget Brickson, William F. Huffman
Publikováno v:
Journal of Medicinal Chemistry. 32:880-884
[1-(beta,beta-Pentamethylene-beta-mercaptopropionic acid),2-(O-ethyl)-D- tyrosine,4-valine,9-desglycine]arginine-vasopressin (SK&F 101926, 1), a potent in vivo and in vitro vasopressin V2 receptor antagonist, was recently tested in human volunteers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00421b7b5c1f996883c9fdea26d7d6f4
https://doi.org/10.1021/jm00124a025
https://doi.org/10.1021/jm00124a025