Zobrazeno 1 - 10
of 182
pro vyhledávání: '"C Quah"'
Autor:
David A. Simon Davis, Melissa Ritchie, Dillon Hammill, Jessica Garrett, Robert O. Slater, Naomi Otoo, Anna Orlov, Katharine Gosling, Jason Price, Desmond Yip, Kylie Jung, Farhan M. Syed, Ines I. Atmosukarto, Ben J. C. Quah
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMachine learning (ML) is a valuable tool with the potential to aid clinical decision making. Adoption of ML to this end requires data that reliably correlates with the clinical outcome of interest; the advantage of ML is that it can model t
Externí odkaz:
https://doaj.org/article/f0ea3aac32394c428ce80fe746b15417
Autor:
Connor H. O’ Meara, Lucy A. Coupland, Farzaneh Kordbacheh, Benjamin J. C. Quah, Chih-Wei Chang, David A. Simon Davis, Anna Bezos, Anna M. Browne, Craig Freeman, Dillon J. Hammill, Pradeep Chopra, Gergely Pipa, Paul D. Madge, Esther Gallant, Courtney Segovis, Angela F. Dulhunty, Leonard F. Arnolda, Imogen Mitchell, Levon M. Khachigian, Ross W. Stephens, Mark von Itzstein, Christopher R. Parish
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Histones, proteins that bind DNA, are toxic for pathogens outside cells but can also cause multi-organ damage as seen in sepsis. Here the authors develop small negatively charged molecules that can be used as histone antidotes, and show that they imp
Externí odkaz:
https://doaj.org/article/47652de3a653433fb4ea511fb90437ea
Autor:
David A Simon Davis, Sahngeun Mun, Julianne M Smith, Dillon Hammill, Jessica Garrett, Katharine Gosling, Jason Price, Hany Elsaleh, Farhan M Syed, Ines I Atmosukarto, Benjamin J C Quah
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264631 (2022)
Clinical adoption of immune checkpoint inhibitors in cancer management has highlighted the interconnection between carcinogenesis and the immune system. Immune cells are integral to the tumour microenvironment and can influence the outcome of therapi
Externí odkaz:
https://doaj.org/article/3da782be15d042aa81990887157ad50b
Autor:
Danushka K. Wijesundara, Wenbo Yu, Ben J. C. Quah, Preethi Eldi, John D. Hayball, Kerrilyn R. Diener, Ilia Voskoboinik, Eric J. Gowans, Branka Grubor-Bauk
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The use of cost-effective vaccines capable of inducing robust CD8+ T cell immunity will contribute significantly towards the elimination of persistent viral infections and cancers worldwide. We have previously reported that a cytolytic DNA v
Externí odkaz:
https://doaj.org/article/458aba626a294f098ff6f9d7d1461b40
Publikováno v:
Environmental Biology of Fishes. 105:55-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc79e63ae7745affd03896704383d8f1
https://doi.org/10.1007/s10641-021-01189-2
https://doi.org/10.1007/s10641-021-01189-2
Akademický článek
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Autor:
David A. Simon Davis, Sahngeun Mun, Julianne M. Smith, Dillon Hammill, Jessica Garrett, Katharine Gosling, Jason Price, Hany Elsaleh, Farhan M. Syed, Ines I. Atmosukarto, Benjamin J. C. Quah
Publikováno v:
PloS one. 17(2)
Clinical adoption of immune checkpoint inhibitors in cancer management has highlighted the interconnection between carcinogenesis and the immune system. Immune cells are integral to the tumour microenvironment and can influence the outcome of therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2801ab7674aa08e029dbe0a3d99103da
https://pubmed.ncbi.nlm.nih.gov/35226704
https://pubmed.ncbi.nlm.nih.gov/35226704
Autor:
Danushka K Wijesundara, Charani Ranasinghe, Ronald J Jackson, Brett A Lidbury, Christopher R Parish, Benjamin J C Quah
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105366 (2014)
Qualitative characteristics of cytotoxic CD8+ T cells (CTLs) are important in measuring the effectiveness of CTLs in controlling HIV-1 infections. Indeed, in recent studies patients who are naturally resistant to HIV-1 infections have been shown to p
Externí odkaz:
https://doaj.org/article/0e731bca0c8e4a89a7b6be79b78c4e03
Autor:
Allen Eng Juh Yeoh, Jing J. Eng, Kean H. Chiew, Ah M. Tan, Germaine S.M. Liew, Shawn H. R. Lee, Koon Mian Foo, Cheryl C.C. Neoh, Joyce Ching Mei Lam, Yiong Huak Chan, Zelia Z.L. Seeto, Bernice L. Z. Oh, Zhi W. Chen, Thuan C. Quah
Publikováno v:
European journal of cancer (Oxford, England : 1990). 142
In non-high-risk (non-HR) patients, the Malaysia-Singapore Acute Lymphoblastic Leukaemia 2003 (MS2003) study achieved good outcomes. However, its delayed-intensification (DI) phase, comprising repeated blocks of protocol III (2003-PIII), was toxic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135c9dad708e591f08baf5df3bc69048
https://pubmed.ncbi.nlm.nih.gov/33246161
https://pubmed.ncbi.nlm.nih.gov/33246161
Akademický článek
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