Voriconazole exposure is influenced by inflammation: A population pharmacokinetic model

Autor: D. Abraham van den Born, Anne-Grete Märtson, Anette Veringa, Nieko C. Punt, Tjip S. van der Werf, Jan-Willem C. Alffenaar, Marieke G.G. Sturkenboom, Daan J. Touw

Publikováno v: International journal of antimicrobial agents, 61:106750. Elsevier Bedrijfsinformatie b.v.

BACKGROUND: Voriconazole is an antifungal drug used for the treatment of invasive fungal infections. Due to highly variable drug exposure, therapeutic drug monitoring (TDM) has been recommended. TDM may be helpful to accurately predict exposure but c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1264e17e5b81f7ec3a4c17377ae5c3
https://research.rug.nl/en/publications/506ac619-c1c0-4565-b1fc-7460c23742fd

FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty

Autor: J.R. Platt, O.M. Todd, P. Hall, Z. Craig, A. Quyn, M. Seymour, M. Braun, J. Roodhart, C. Punt, N. Christou, J. Taieb, M. Karoui, J. Brown, D.A. Cairns, D. Morton, A. Gilbert, J.F. Seligmann

Publikováno v: R Platt, J, M Todd, O, Hall, P S, Craig, Z, Quyn, A, Seymour, M, Braun, M, Roodhart, J, Punt, C, Christou, N, Taieb, J, Karoui, M, Brown, J, A Cairns, D, Morton, D, Gilbert, A & F Seligmann, J 2022, ' FOxTROT2: Innovative Trial Design to Evaluate the Role of Neoadjuvant Chemotherapy for Treating Locally Advanced Colon Cancer in Older Adults or those with Frailty ', ESMO Open . https://doi.org/10.1016/j.esmoop.2022.100642

Treating older adults with cancer is increasingly important in modern oncology practice. However, we currently lack the high-quality evidence needed to guide optimal management of this heterogeneous group. Principally, historic under-recruitment of o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c32416460402a2fe7115c9a8c94a7ca
https://pubmed.ncbi.nlm.nih.gov/36549127

Menstrual problems in chronic immune thrombocytopenia: A monthly challenge - a cohort study and review

Autor: Wobke E. M. van Dijk, Marieke C. Punt, Karin P. M. van Galen, Jeanette van Leeuwen, A. Titia Lely, Roger E. G. Schutgens

Publikováno v: British journal of haematology. 198(4)

Immune thrombocytopenia (ITP) may cause menstrual problems. This cross-sectional study assessed menstrual problems in premenopausal chronic ITP women by several questionnaires, including the pictorial bleeding assessment calendar (PBAC; score ≥100

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe984b9f38a108de1f117097af61f799
https://pubmed.ncbi.nlm.nih.gov/35662003

Menstrual and obstetrical bleeding in women with inherited platelet receptor defects—A systematic review

Autor: Karin P M van Galen, Kitty W. M. Bloemenkamp, Marieke C. Punt, Idske C L Kremer Hovinga, Pauline C E Schuitema

Publikováno v: Haemophilia

Introduction Women with inherited platelet receptor defects (IPRD) may have an increased risk of heavy menstrual bleeding (HMB) and postpartum haemorrhage (PPH). Aim To present a systematic overview of the literature on the prevalence and management

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9147ab4b33e9a3d1413ce601d2e53ab4
https://doi.org/10.1111/hae.13927

A qualitative study on the experiences of haemophilia carriers before, during and after pregnancy

Autor: Mariette H E Driessens, Lynnda Pekel, Lorynn Teela, Karin P M van Galen, A. Titia Lely, Krista Fischer, Kitty W. M. Bloemenkamp, Lotte Haverman, Marieke C Punt

Publikováno v: Haemophilia, 27(6), e675-e682. Wiley-Blackwell

Introduction Haemophilia carriers (HCs) face considerable haemostatic and psychological challenges during reproduction. Aim To explore the perspectives of HCs on healthcare in the current standard of haemophilia treatment during all reproductive phas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e4f6e428f4b287e16d07576462d690
https://doi.org/10.1111/hae.14396