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pro vyhledávání: '"C Pothoulakis"'
Akademický článek
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Autor:
E. Im, C. Pothoulakis
Publikováno v:
Gastroentérologie Clinique et Biologique. 34:67-75
Resume La presente revue resume les mecanismes d’action probiotiques de Saccharomyces boulardii ( S. boulardii ) vis-a-vis des situations inflammatoires ou non inflammatoires associees a une diarrhee. S. boulardii est distribue sous forme lyophilis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d117a374af3192c99f7a7fb8d3a968
https://doi.org/10.1016/s0399-8320(10)70010-5
https://doi.org/10.1016/s0399-8320(10)70010-5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Pierre Michetti, Michel Warny, Samer Aboudola, Ciaran P. Kelly, J. Thomas Lamont, C Pothoulakis, Amir A. Qamar
Publikováno v:
Infection and Immunity. 69:2762-2765
Saccharomyces boulardiiis a nonpathogenic yeast that protects against antibiotic-associated diarrhea and recurrentClostridium difficilecolitis. The administration ofC. difficiletoxoid A by gavage toS. boulardii-fed BALB/c mice caused a 1.8-fold incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66350b581963105936c9d12b54ff1e1a
https://doi.org/10.1128/iai.69.4.2762-2765.2001
https://doi.org/10.1128/iai.69.4.2762-2765.2001
Autor:
J. Thomas Lamont, Ciaran P. Kelly, Michel Warny, Ignazio Castagliuolo, Jeff K. Zacks, Andrew C. Keates, Samer Aboudola, Amir A. Qamar, C Pothoulakis, Sarah Keates
Publikováno v:
Scopus-Elsevier
Clostridium difficile toxin A causes acute neutrophil infiltration and intestinal mucosal injury. In cultured cells, toxin A inactivates Rho proteins by monoglucosylation. In monocytes, toxin A induces IL-8 production and necrosis by unknown mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a0ef9f014dd3322988418b0d84ada9
https://doi.org/10.1172/jci7545
https://doi.org/10.1172/jci7545
Autor:
D C Laine, Michel Warny, Ciaran P. Kelly, C Pothoulakis, F Lebel, A Fatimi, E F Bostwick, J T LaMont
Publikováno v:
Gut. 44:212-217
BackgroundBovine immunoglobulin concentrate (BIC)-Clostridium difficile is prepared from the colostrum of cows immunised againstC difficile toxins and contains high concentrations of neutralising IgG antitoxin.AimsTo determine the proportion of BIC-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e046ca79054ea10a4e489d53dda6a5c
https://doi.org/10.1136/gut.44.2.212
https://doi.org/10.1136/gut.44.2.212
Autor:
Andrew C. Keates, C Pothoulakis, Ciaran P. Kelly, Michel Warny, Sarah Keates, Joanne K. Linevsky, J. Thomas Lamont
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 273:G1333-G1340
Neutrophil infiltration is central to the pathogenesis of Clostridium difficiletoxin A-induced enterocolitis. This study examines whether monocyte activation by C. difficile toxins is instrumental in initiating neutrophil activation and recruitment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cfd32aa64c6b62ffde3e7a074cab4b
https://doi.org/10.1152/ajpgi.1997.273.6.g1333
https://doi.org/10.1152/ajpgi.1997.273.6.g1333
Autor:
Ciaran P. Kelly, Michel Warny, Ignazio Castagliuolo, C Pothoulakis, Sarah Keates, J Salcedo, J T LaMont
Publikováno v:
Scopus-Elsevier
Background—Many individuals have serum antibodies against Clostridium difficile toxins. Those with an impaired antitoxin response may be susceptible to recurrent, prolonged, or severe C difficile diarrhoea and colitis.Aims—To examine whether trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749be6574a40a3002c2247c10e4c88fe
https://doi.org/10.1136/gut.41.3.366
https://doi.org/10.1136/gut.41.3.366
Autor:
C Pothoulakis, TA Brasitus, Ignazio Castagliuolo, Ciaran P. Kelly, J T LaMont, U Galili, PK Dudeja, S Nikulasson
Publikováno v:
Gastroenterology. 110:1704-1712
BACKGROUND & AIMS: Nearly all human sera contain an immunoglobulin G antibody (antigalactose) that binds the trisaccharide Gal alpha 1-3Gal beta 1-4GlcNAc expressed on cells from most mammals but not humans. Because the Clostridium difficile toxin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f36984e5336f23a72d5292b3d31ede
https://doi.org/10.1053/gast.1996.v110.pm8964394
https://doi.org/10.1053/gast.1996.v110.pm8964394
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 268:G487-G495
The principal cellular response to Clostridium difficile toxin B, a protein toxin associated with antibiotic-associated colitis, is the disassembly of actin microfilaments. Although receptor-activated signal transduction mechanisms have been proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dae9ef59618fcfedd3fb719df098ac6
https://doi.org/10.1152/ajpgi.1995.268.3.g487
https://doi.org/10.1152/ajpgi.1995.268.3.g487