Zobrazeno 1 - 10
of 107
pro vyhledávání: '"C Pelassy"'
Publikováno v:
The Journal of Immunology. 157:1468-1473
The mechanism by which calcium-depleted intracellular stores may trigger an external calcium influx through a calcium release-activated channel was investigated by analyzing the effects of several protein tyrosine kinase inhibitors on calcium movemen
Publikováno v:
The Journal of Immunology. 151:119-127
We had previously reported that the CD29 mAb "K20," presented in a soluble form, blocks peripheral T cell proliferation/activation induced by a CD3 mAb. To better characterize the negative signal delivered by soluble K20, we have investigated its eff
Autor:
C, Pelassy, C, Aussel
Publikováno v:
Pharmacology. 47(1)
The effects of quinine, quinidine, cinchonine, cinchonidine and chloroquine on phospolipid synthesis in the Jurkat T cell line have been compared. It was found that the two potassium channel blockers, quinine and quinidine, markedly enhanced phosphat
Publikováno v:
Journal of lipid mediators. 7(2)
In the human T cell line Jurkat, three drugs generally used as effectors of K+ channels, i.e., quinine, 4-aminopyridine and tetraethylammonium, modify phospholipid metabolism. The drugs inhibited the synthesis of both phosphatidylcholine and phosphat
Publikováno v:
Journal of lipid mediators. 5(3)
A monoclonal antibody, B66.6, previously classified in the cluster of differentiation 4 (CD4), has been studied and compared with another CD4 monoclonal antibody, IOT4. It was found that B66.6 but not IOT4 was able to mobilize Ca2+ from intracellular
Publikováno v:
Journal of lipid mediators. 4(2)
Phosphatidic acid exogenously added to Jurkat T-cells, provokes a marked inhibition of phosphatidylserine (PS) synthesis. Comparison of the efficiency of synthetic phosphatidic acids, differing in their fatty acid content, to induce inhibition of PS-
Calcium-dependent regulation of phosphatidylserine synthesis in control and activated Jurkat T cells
Publikováno v:
Journal of lipid mediators. 3(3)
Activation of Jurkat T cells with phytohemagglutinin (PHA), CD3 or CD2 monoclonal antibodies (mAbs) results in a marked inhibition of phosphatidylserine (PS) synthesis. Activation of Jurkat T cells with PHA in a Ca(2+)-free medium resulted in an arre
Publikováno v:
Journal of lipid mediators. 3(1)
Phosphatidylserine has been implicated both in the regulation of protein kinase C activity and in the regulation of T lymphocyte activation. Taking into account the fact that some serine analogues modify the activity of the base exchange enzyme syste
Autor:
Anna Roca, C. Pelassy, Lourdes Places, Francisco Lozano, Claude Aussel, Javier Calvo, Maria Simarro
Publikováno v:
Immunology Letters. 56:59
Publikováno v:
The EMBO Journal. 6:1301-1307
A transforming sequence was identified using co-transfection of DNA from the human mammary carcinoma cell line MCF-7 and of a G418 resistance gene into NIH 3T3 cells, followed by tumor formation in athymic mice. This sequence, named mcf.2, was molecu