Zobrazeno 1 - 10
of 16
pro vyhledávání: '"C P Yap"'
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer
Autor:
Ritu Yadav, Rinku Khatkar, Kenneth C-H Yap, Chloe Yun-Hui Kang, Juncheng Lyu, Rahul Kumar Singh, Surojit Mandal, Adrija Mohanta, Hiu Yan Lam, Elena Okina, Rajiv Ranjan Kumar, Vivek Uttam, Uttam Sharma, Manju Jain, Hridayesh Prakash, Hardeep Singh Tuli, Alan Prem Kumar, Aklank Jain
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Lung cancer is a severe challenge to the health care system with intrinsic resistance to first and second-line chemo/radiotherapies. In view of the sterile environment of lung cancer, several immunotherapeutic drugs including nivolumab, pemb
Externí odkaz:
https://doaj.org/article/8d24362bca0a4f9ab5e76ee509aef09c
Autor:
Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-37 (2023)
Abstract The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell cycle progression. Growth factor signalling to transcription factors in the PA
Externí odkaz:
https://doaj.org/article/9b643e4724194798a585634205af8fef
Autor:
Sabrina Pit, Malcolm Fisk, Winona Freihaut, Fashola Akintunde, Bamidele Aloko, Britta Berge, Anne Burmeister, Adriana Ciacâru, Jürgen Deller, Rae Dulmage, Tae Hwa Han, Qiang Hao, Peter Honeyman, Peter C. Huber, Thomas Linner, Stefan Lundberg, Mofoluwaso Nwamara, Kamolpun Punpuing, Jennifer Schramm, Hajime Yamada, Jason C. H. Yap
Publikováno v:
International Journal for Equity in Health, Vol 20, Iss 1, Pp 1-22 (2021)
Abstract Background COVID-19 has a direct impact on the employment of older people. This adds to the challenge of ageism. The World Health Organization has started a worldwide campaign to combat ageism and has called for more research and evidence-ba
Externí odkaz:
https://doaj.org/article/c95f097012d64bf9bf675cb678a67063
Publikováno v:
Healthcare, Vol 11, Iss 11, p 1546 (2023)
A projected rise in patients with complex health needs and a rapidly ageing population will place an increased burden on the healthcare system. Care coordination can bridge potential gaps during care transitions and across the care continuum to facil
Externí odkaz:
https://doaj.org/article/238d6871d1374b92adfe7a31851ba14c
Autor:
Mark D. Muthiah, Melissa Sin Hui Chua, Konstadina Griva, Ivan Low, Wen Hui Lim, Cheng Han Ng, Jeff Y. F. Hwang, Jason C. H. Yap, Shridhar G. Iyer, Glenn K. Bonney, Vathsala Anantharaman, Daniel Q. Huang, Eunice Xiang-Xuan Tan, Guan-Huei Lee, Alfred W. C. Kow, Bee Choo Tai
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Background: Organ shortage is still a world-wide problem, resulting in long waiting lists for kidney, liver, and heart transplant candidates across many transplant centers globally. This has resulted in the move toward presumed consent to increase de
Externí odkaz:
https://doaj.org/article/436d62e9a9ca4dcb96827119846f95f1
Autor:
Heinz Haas, Dmitry Zyabkin, Juliana Schell, Thien T. Dang, Ian C. J. Yap, Ilaria Michelon, Daniel Gaertner, Adeleh Mokhles Gerami, Cornelia Noll, Reinhard Beck
Publikováno v:
Crystals, Vol 12, Iss 8, p 1064 (2022)
The electric-field gradient (EFG) at nuclei in solids is a sensitive probe of the charge distribution. Experimental data, which previously only existed in insulators, have been available for metals with the development of nuclear measuring techniques
Externí odkaz:
https://doaj.org/article/3f36c37fad6b4efbbaee53704e9e3514
Publikováno v:
The Journal of the Royal College of Physicians of Edinburgh. 42:306-310
Background We believe that there is a need to increase awareness, particularly among foundation year doctors, of the importance of performing a full neurological examination, including ophthalmoscopy, in medical inpatients. Following a serious unexpe
Publikováno v:
Proceedings of the 21th International Symposium on the Physical and Failure Analysis of Integrated Circuits (IPFA).
Publikováno v:
International Symposium for Testing and Failure Analysis.
Wafer level tester-based fault isolation (FI) tool exists back in 2008 but is not widely adopted by industry. This is expected because such tool is commonly known for its primary role in dynamic electrical FI. Since packages are readily available, th
Publikováno v:
Proceedings of the 20th IEEE International Symposium on the Physical and Failure Analysis of Integrated Circuits (IPFA).
Scan diagnosis based fault isolation technique using Electronic Design Automation (EDA) software tool is highly effective and commonly adopted for product chain and logic yield learning. For every new device introduction, prior to implementation of s