[Tryptase, a marker for the activation and localization of mast cells]

Autor: D, Ludolph-Hauser, F, Ruëff, C P, Sommerhoff, B, Przybilla

Publikováno v: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 50(8)

The serine protease tryptase (ECNr. 3.4. 21.59), which is almost exclusively expressed in mast cells, is released by mast cell degranulation in an enzymatically active form together with other mediators, e.g. histamine, into the extracellular space a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b705dfef133da94d6f68694bd91fd66b
https://pubmed.ncbi.nlm.nih.gov/10460298

The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition

Autor: M T, Stubbs, R, Morenweiser, J, Stürzebecher, M, Bauer, W, Bode, R, Huber, G P, Piechottka, G, Matschiner, C P, Sommerhoff, H, Fritz, E A, Auerswald

Publikováno v: The Journal of biological chemistry. 272(32)

The x-ray crystal structure of recombinant leech-derived tryptase inhibitor (rLDTI) has been solved to a resolution of 1.9 A in complex with porcine trypsin. The nonclassical Kazal-type inhibitor exhibits the same overall architecture as that observe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::16d9165158f78d7177ea14df8824ca96
https://pubmed.ncbi.nlm.nih.gov/9242660

Inhibition of histamine release from human mast cells ex vivo by natural and synthetic chymase inhibitors

Autor: S C, Dietze, C P, Sommerhoff, H, Fritz

Publikováno v: Biological chemistry Hoppe-Seyler.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3071f2efcd42c3f69f61953d3c46a79
https://pubmed.ncbi.nlm.nih.gov/1698069

Conformationally constrained cyclic grafted peptidomimetics targeting protein–protein interactions.

Autor: Dahal, Achyut¹ (AUTHOR), Subramanian, Vivekanandan² (AUTHOR), Shrestha, Prajesh^1,3 (AUTHOR), Liu, Dong⁴ (AUTHOR), Gauthier, Ted⁴ (AUTHOR), Jois, Seetharama^1,3 (AUTHOR) sjois@lsu.edu

Publikováno v: Peptide Science. Sep2023, Vol. 115 Issue 5, p1-11. 11p.

Synthetic Approaches of Epoxysuccinate Chemical Probes.

Autor: Nicolau I; University of Bucharest, Faculty of Chemistry, Department of Organic Chemistry, Biochemistry and Catalysis, Research Centre of Applied Organic Chemistry, 90 Panduri Street, 050663, Bucharest, Romania., Hădade ND; Babes-Bolyai University, Faculty of Chemistry and Chemical Engineering, Supramolecular and Organometallic Chemistry Centre, 11 Arany Janos Street, 400028, Cluj-Napoca, Romania., Matache M; University of Bucharest, Faculty of Chemistry, Department of Organic Chemistry, Biochemistry and Catalysis, Research Centre of Applied Organic Chemistry, 90 Panduri Street, 050663, Bucharest, Romania., Funeriu DP; University of Bucharest, Faculty of Chemistry, Department of Organic Chemistry, Biochemistry and Catalysis, Research Centre of Applied Organic Chemistry, 90 Panduri Street, 050663, Bucharest, Romania.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 Aug 15; Vol. 24 (16), pp. e202300157. Date of Electronic Publication: 2023 Jul 21.