Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C P Sheehan"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128636 (2015)
Although type I interferons (IFNs) were first described almost 60 years ago, the ability to monitor and modulate the functional activities of the individual IFN subtypes that comprise this family has been hindered by a lack of reagents. The major typ
Externí odkaz:
https://doaj.org/article/ffc145d0248048a0b0f3501c2560ea31
Autor:
Grzegorz B Gmyrek, Holly M Akilesh, Daniel B Graham, Anja Fuchs, Lihua Yang, Mark J Miller, Gabriel J Sandoval, Kathleen C F Sheehan, Robert D Schreiber, Michael S Diamond, Wojciech Swat
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76145 (2013)
Dap12 and FcRγ, the two transmembrane ITAM-containing signaling adaptors expressed in dendritic cells (DC), are implicated in the regulation of DC function. Several activating and adhesion receptors including integrins require these chains for their
Externí odkaz:
https://doaj.org/article/bb4f9cdcd8674162b5295e3728b7038e
Autor:
Amelia K Pinto, Stephane Daffis, James D Brien, Maria D Gainey, Wayne M Yokoyama, Kathleen C F Sheehan, Kenneth M Murphy, Robert D Schreiber, Michael S Diamond
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002407 (2011)
A genetic absence of the common IFN-α/β signaling receptor (IFNAR) in mice is associated with enhanced viral replication and altered adaptive immune responses. However, analysis of IFNAR(-/-) mice is limited for studying the functions of type I IFN
Externí odkaz:
https://doaj.org/article/15251df72baf4044a37494cd5b83a3c2
Autor:
C P Sheehan, N D Christofides
Publikováno v:
Clinical Chemistry. 41:17-23
We describe the development and validation of a one-step nonradioactive immunoassay for free thyroxine (Amerlite-MAB FT4) in serum or plasma, in the dedicated Amerlite enhanced luminescence assay system. A monoclonal antibody to thyroxine (T4), conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93d463844db8ebc1c405666f18ff3f52
https://doi.org/10.1093/clinchem/41.1.17
https://doi.org/10.1093/clinchem/41.1.17
Autor:
N D Christofides, C P Sheehan
Publikováno v:
Clinical Chemistry. 41:24-31
The technical and diagnostic performance of the Amerlite-MAB enhanced luminescence assay for free thyroxine (FT4) was assessed in a multicenter evaluation trial. The euthyroid central 95% reference range for FT4 (1393 subjects) was 11.5-27.7 pmol/L (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2339ec07fb8412a530df5b498142c6
https://doi.org/10.1093/clinchem/41.1.24
https://doi.org/10.1093/clinchem/41.1.24
One-Step, Labeled-Antibody Assay for Measuring Free Thyroxin. II. Performance in a Multicenter Trial
Autor:
C P Sheehan, N D Christofides
Publikováno v:
Clinical Chemistry. 38:19-25
The technical and diagnostic performance of a labeled antibody radioassay for free thyroxin (Amerlex-MAB* FT4) was examined in a multicenter trial. The overall mean within-assay precision (CV) in eight centers was 6.2% at 30 pmol/L and 3.6% at 13 pmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f921245bb281086c776afa313f061da1
https://doi.org/10.1093/clinchem/38.1.19
https://doi.org/10.1093/clinchem/38.1.19
Publikováno v:
Clinical Chemistry. 38:11-18
We describe a one-step, labeled-antibody radioassay for measuring free thyroxin (FT4) in serum or plasma, based on a novel principle. FT4 in the sample competes with a gross molar excess (over antibody) of a cross-reactant (L-triiodothyronine, T3), c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd18f9b1417a7fe6dc47a187b148575
https://doi.org/10.1093/clinchem/38.1.11
https://doi.org/10.1093/clinchem/38.1.11
Publikováno v:
Clinical Chemistry. 36:765-771
Free thyroxin (FT4) estimates by two immunoassays were compared with the concentrations of albumin in serum of apparently euthyroid subjects who either were (n = 99) or were not (n = 327) suffering from severe nonthyroidal illness (sNTI). In neither
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4361a87cd790cf29e4c6976d2494a21f
https://doi.org/10.1093/clinchem/36.5.765
https://doi.org/10.1093/clinchem/36.5.765
Autor:
N D, Christofides, C P, Sheehan
Publikováno v:
Clinical chemistry. 41(1)
We describe the development and validation of a one-step nonradioactive immunoassay for free thyroxine (Amerlite-MAB FT4) in serum or plasma, in the dedicated Amerlite enhanced luminescence assay system. A monoclonal antibody to thyroxine (T4), conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::644cd49facce4692c15b24a4efe47317
https://pubmed.ncbi.nlm.nih.gov/7813074
https://pubmed.ncbi.nlm.nih.gov/7813074
Publikováno v:
Clinical chemistry. 38(1)
We describe a one-step, labeled-antibody radioassay for measuring free thyroxin (FT4) in serum or plasma, based on a novel principle. FT4 in the sample competes with a gross molar excess (over antibody) of a cross-reactant (L-triiodothyronine, T3), c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f901750e7547c387dce1c396aedaa20a
https://pubmed.ncbi.nlm.nih.gov/1424150
https://pubmed.ncbi.nlm.nih.gov/1424150