CNTools: A computational toolbox for cellular neighborhood analysis from multiplexed images.

Autor: Yicheng Tao, Fan Feng, Xin Luo, Conrad V Reihsmann, Alexander L Hopkirk, Jean-Philippe Cartailler, Marcela Brissova, Stephen C J Parker, Diane C Saunders, Jie Liu

Publikováno v: PLoS Computational Biology, Vol 20, Iss 8, p e1012344 (2024)

Recent studies show that cellular neighborhoods play an important role in evolving biological events such as cancer and diabetes. Therefore, it is critical to accurately and efficiently identify cellular neighborhoods from spatially-resolved single-c

Externí odkaz: https://doaj.org/article/fa5d8a4580c940c98d6914fa30f9c20e

Neutron-upscattering enhancement of the triple-alpha process

Autor: J. Bishop, C. E. Parker, G. V. Rogachev, S. Ahn, E. Koshchiy, K. Brandenburg, C. R. Brune, R. J. Charity, J. Derkin, N. Dronchi, G. Hamad, Y. Jones-Alberty, Tz. Kokalova, T. N. Massey, Z. Meisel, E. V. Ohstrom, S. N. Paneru, E. C. Pollacco, M. Saxena, N. Singh, R. Smith, L. G. Sobotka, D. Soltesz, S. K. Subedi, A. V. Voinov, J. Warren, C. Wheldon

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-5 (2022)

The triple-alpha process plays a role in nucleosynthesis, in the formation of 12C. Here, the authors discuss the rate and role of the neutron upscattering phenomenon on the triple-alpha process in a multi-step process.

Externí odkaz: https://doaj.org/article/1a41d4cd95b14b239e9690f1b14ccf60

Chromatin information content landscapes inform transcription factor and DNA interactions

Autor: Ricardo D’Oliveira Albanus, Yasuhiro Kyono, John Hensley, Arushi Varshney, Peter Orchard, Jacob O. Kitzman, Stephen C. J. Parker

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Interaction between transcription factors and chromatin is fundamental for genome organization and regulation. Here, the authors use information theory to measure signatures of organized chromatin resulting from transcription factor-chromatin interac

Externí odkaz: https://doaj.org/article/50eaff8488d344aaafb37f1d19c687ba

BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning

Autor: Tongyu Liu, Lin Mi, Jing Xiong, Peter Orchard, Qi Yu, Lei Yu, Xu-Yun Zhao, Zhuo-Xian Meng, Stephen C. J. Parker, Jiandie D. Lin, Siming Li

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

The regulatory networks that govern chromatin accessibility and gene expression in brown and beigeadipocytes remain to be fully elucidated. Here the authors use fat-specific inactivation of BAF60a toreveal a differential role for this chromatin remod

Externí odkaz: https://doaj.org/article/9367a3385a00407688e6ae5ad541e1f3

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Autor: M. Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M. Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L. Koller, Zoltán Kutalik, Jian’an Luan, Ida Malkin, Janina S. Ried, Albert V. Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi, Kristina Åkesson, Najaf Amin, Leslie J. Baier, Inês Barroso, David A. Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B. Borecki, Aron S. Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A. Cauley, Peggy M. Cawthon, Henna Cederberg, Zhao Chen, Nam H. Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R. Cummings, Philip L. De Jager, Ilja Demuth, Rosalie A. M. Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W. Enneman, Mike Erdos, Johan G. Eriksson, Joel Eriksson, Karol Estrada, Daniel S. Evans, Mary F. Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L. Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L. Hanson, Caroline Hayward, Albert Hofman, Eric P. Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J. Hubal, Alan Hubbard, Kim M. Huffman, Lise B. Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M. Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O. Kilpeläinen, Norman Klopp, Jacqueline S. L. Kloth, Heikki A. Koistinen, William E. Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L. Langdahl, Lenore J. Launer, Jong-Young Lee, Markus M. Lerch, Joshua R. Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Östen Ljunggren, Mattias Lorentzon, Robert N. Luben, William Maixner, Fiona E. McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Håkan Melhus, Dan Mellström, Simon Melov, Karl Michaëlsson, Braxton D. Mitchell, Andrew P. Morris, Leif Mosekilde, Anne Newman, Carrie M. Nielson, Jeffrey R. O’Connell, Ben A. Oostra, Eric S. Orwoll, Aarno Palotie, Stephen C. J. Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L. Prince, Katri Räikkönen, Stuart H. Ralston, Samuli Ripatti, John A. Robbins, Jerome I. Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E. Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stančáková, Elisabeth Steinhagen-Thiessen, Elizabeth A. Streeten, Unnur Styrkarsdottir, Karin M. A. Swart, Sian-Tsung Tan, Mark A. Tarnopolsky, Patricia Thompson, Cynthia A. Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J. Tranah, Jaakko Tuomilehto, Natasja M. van Schoor, Arjun Verma, Peter Vollenweider, Henry Völzke, Jean Wactawski-Wende, Mark Walker, Michael N. Weedon, Ryan Welch, H.-Erich Wichmann, Elisabeth Widen, Frances M. K. Williams, James F. Wilson, Nicole C. Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C. Chambers, Angela Döring, Cornelia M. van Duijn, Michael J. Econs, Vilmundur Gudnason, Jaspal S. Kooner, Bruce M. Psaty, Timothy D. Spector, Kari Stefansson, Fernando Rivadeneira, André G. Uitterlinden, Nicholas J. Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J. F. Loos, David Karasik, Tamara B. Harris, Claes Ohlsson, Douglas P. Kiel

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-4 (2017)

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Externí odkaz: https://doaj.org/article/dba3bf37aec64af2a93c8d1bb6cfdcb4