Výsledky vyhledávání - "C P Martucci"

Distinct forms of hepatic androgen 6β-hydroxylase induced in the rat by indole-3-carbinol and pregnenolone carbonitrile

Autor: Anne-Marie Newcombe, Peter H. Jellinck, P G Forkert, C P Martucci

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 51:219-225

The ability of indole-3-carbinol (IC), an anticarcinogen present in cruciferous vegetables, to induce CYP1A1, CYP1A2, CYP2B1/2, CYP2E1 and CYP3A1/2 in female rat liver was determined by Western analysis using monoclonal antibodies and compared to eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b5d3e0b0db48377a0fbe4051b95dda
https://doi.org/10.1016/0960-0760(94)90096-5

Zobrazit plný text záznamu

The effects of polyoxyethylated cholesterol on fecal bile acids and nitrogen and on cholesterol balance in rats

Autor: N. R. Stevenson, C. P. Martucci, Avedis K. Khachadurian, Louis F. Amorosa

Publikováno v: Lipids. 26:209-212

Polyoxyethylated cholesterol (POEC) is a water soluble derivative of cholesterol which decreases cholesterol absorption in rats without affecting body weight, fatty acid excretion, or intestinal histology. In the present study rat feces were analyzed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a7e8ea7213690bfc418fc03a28d9d8
https://doi.org/10.1007/bf02543973

Zobrazit plný text záznamu

16 alpha-hydroxylation of estradiol: a possible risk marker for breast cancer

Autor: Richard J. Hershcopf, C P Martucci, H. L. Bradlow, Jerry H. Fishman

Publikováno v: Annals of the New York Academy of Sciences. 464

From these results we may conclude that estradiol 16 alpha-hydroxylation is highly correlated with tumor incidence, and that the reaction is partly regulated by MMTV and the rest by genetic influences. Elevated hydroxylation appears to be an autosoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3eb190e120baa1ee07f201b030c40b
https://pubmed.ncbi.nlm.nih.gov/3014947

Zobrazit plný text záznamu

Estradiol 16 alpha-hydroxylation in the mouse correlates with mammary tumor incidence and presence of murine mammary tumor virus: a possible model for the hormonal etiology of breast cancer in humans

Autor: C P Martucci, H. L. Bradlow, Jay A. Fishman, Richard J. Hershcopf

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 82(18)

In this report, we describe our findings on the relationship between estradiol 16 alpha-hydroxylation and mammary tumor incidence. A close correlation between the two has been demonstrated with 16-hydroxylation being elevated in strains with a high i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8318f8658c6b936e7b326308aeed193c
https://pubmed.ncbi.nlm.nih.gov/2994069

Zobrazit plný text záznamu

New Concepts of Estrogenic Activity: the Role of Metabolites in the Expression of Hormone Action

Autor: C. P. Martucci, J. Fishman

Publikováno v: The Menopause and Postmenopause ISBN: 9789401172325

The most striking and possibly the most significant hormonal change associated with the menopause is the cessation of estrogen secretion by the ovaries. The resultant sharp decrease in circulating estrogens has been presumed to be causally related to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72bbd17ab47a50927c4f8d84edf2266d
https://doi.org/10.1007/978-94-011-7230-1_5