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A novel bioassay to detect Nociceptin/Orphanin FQ release from single human polymorphonuclear cells.
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268868 (2022)
Nociceptin/Orphanin FQ (N/OFQ) is the endogenous opioid agonist for the N/OFQ receptor or NOP. This receptor system is involved in pain processing but also has a role in immune regulation. Indeed, polymorphonuclear cells (PMNs) express mRNA for N/OFQ
Externí odkaz:
https://doaj.org/article/5eed6c00273f40869b5e8cb25e1e8b46