Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C P Carron"'
We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a8ddfd71df5da3a8e45257fe45409e
https://ora.ox.ac.uk/objects/uuid:4d2fed34-afab-40ce-9599-098f6b0ed6cc
https://ora.ox.ac.uk/objects/uuid:4d2fed34-afab-40ce-9599-098f6b0ed6cc
Publikováno v:
Journal of Biological Chemistry. 273:22113-22119
The crystal structures of the I domains of integrins MAC-1 (alphaM beta2; CD11b/CD18) and LFA-1 (alphaL beta2; CD11a/CD18) show that a single conserved cation-binding site is present in each protein. Purified recombinant I domains have intrinsic liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b6b280de78ed6332825640460390f60
https://doi.org/10.1074/jbc.273.34.22113
https://doi.org/10.1074/jbc.273.34.22113
Autor:
David G. Corley, Edwin Rowold, C P Carron, Margie S. Hunter, Richard C. Durley, Brian F. Kilpatrick
Publikováno v:
Journal of Natural Products. 60:894-899
Four new clerodane diterpenes, casearinols A and B (1 and 2) and casearinones A and B (3 and 4), were isolated from the leaves of Casearia guianensis. These immunomodulatory compounds have been structurally elucidated primarily on the basis of 2D NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379115f4fe32aeb2e5ccb7bafa4b9285
https://doi.org/10.1021/np970141n
https://doi.org/10.1021/np970141n
Publikováno v:
Protein Expression and Purification. 5:498-508
LFA-1/ICAM-1 interaction is important in facilitating a number of cellular events including antigen-specific T-cell activation and leukocyte transendothelial migration. We are interested in defining residues and contact sites that mediate ICAM-1 inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e18cc5c017363e416081f41dae752f2
https://doi.org/10.1006/prep.1994.1069
https://doi.org/10.1006/prep.1994.1069
Autor:
C P Carron, Michael F. Rafferty, Debra M. Meyer, Patrick M. Beardsley, Linda L. Tam, Susan A. Nash, Nizal S. Chandrakumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:309-312
A simple method for the stereo-controlled preparation of phenylphosphonate monoesters which are transition state mimics for the hydrolysis of the benzoic acid ester moiety of cocaine is described. Some preliminary results on the use of these mimics f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec96bf8f2fd849e196a41c67ed28d0e
https://doi.org/10.1016/s0960-894x(01)80899-4
https://doi.org/10.1016/s0960-894x(01)80899-4
Autor:
C Carr, Roger C. Wiegand, C A Langner, J I Gordon, Robert J. Duronio, J C Minnerly, C P Carron, Adele M. Pauley
Publikováno v:
Journal of Biological Chemistry. 267:8591-8598
Myristoyl-CoA:protein N-myristoyltransferase (NMT) has recently been identified as a target for antiviral and antifungal therapy. Candida albicans is a dimorphic, asexual yeast that is a major cause of systemic fungal infections in immunosuppressed h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94e6874a2e589fc6f6c80884ab5e6bed
https://doi.org/10.1016/s0021-9258(18)42484-2
https://doi.org/10.1016/s0021-9258(18)42484-2
Autor:
G A Nickols, Debra M. Meyer, Peter G. Ruminski, J G Rico, C P Carron, R L Ornberg, William F. Westlin, V W Engleman
Publikováno v:
The Journal of endocrinology. 165(3)
Osteoclasts are actively motile on bone surfaces and undergo alternating cycles of migration and resorption. Osteoclast interaction with the extracellular matrix plays a key role in the osteoclast resorptive process and a substantial body of evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4674bca64b2c5c35b4de4afb6e91b844
https://pubmed.ncbi.nlm.nih.gov/10828842
https://pubmed.ncbi.nlm.nih.gov/10828842
Autor:
C P, Carron, D M, Meyer, J A, Pegg, V W, Engleman, M A, Nickols, S L, Settle, W F, Westlin, P G, Ruminski, G A, Nickols
Publikováno v:
Cancer research. 58(9)
The integrin alpha(v)beta3 interacts with the arginine-glycine-aspartic acid (RGD) tripeptide recognition sequence of a variety of extracellular matrix proteins. Recent studies show that alpha(v)beta3 plays an important role in tumor-induced angiogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::723536788f9adc75b5007c6fd027b69a
https://pubmed.ncbi.nlm.nih.gov/9581835
https://pubmed.ncbi.nlm.nih.gov/9581835
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(6)
We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::608c31a5fd6cccb98a679c20bc43fc9c
https://pubmed.ncbi.nlm.nih.gov/9300688
https://pubmed.ncbi.nlm.nih.gov/9300688
Autor:
R C, Wiegand, C, Carr, J C, Minnerly, A M, Pauley, C P, Carron, C A, Langner, R J, Duronio, J I, Gordon
Publikováno v:
The Journal of biological chemistry. 267(12)
Myristoyl-CoA:protein N-myristoyltransferase (NMT) has recently been identified as a target for antiviral and antifungal therapy. Candida albicans is a dimorphic, asexual yeast that is a major cause of systemic fungal infections in immunosuppressed h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fccefcb7557b6df74bb5e84c1b211fc0
https://pubmed.ncbi.nlm.nih.gov/1569105
https://pubmed.ncbi.nlm.nih.gov/1569105