Zobrazeno 1 - 10 of 14 pro vyhledávání: '"C P, Sabaitis"'
1
Validation of intratracheal instillation as an alternative for aerosol inhalation toxicity testing
Autor: C. S. Aaron, D. A. Rop, B. K. J. Leong, C. P. Sabaitis
Publikováno v: Journal of Applied Toxicology. 19:133-140
In collecting inhalation toxicity data for the evaluation of the health hazard from occupational exposure to the aerosols of a drug or a chemical, the determination of the inhaled dose in relation to the animal response is most desirable. Intratrache
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58071ff57bf8f17895104ff457e023ce
https://doi.org/10.1002/(sici)1099-1263(199903/04)19:2<133::aid-jat549>3.0.co
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2
Quantitative morphometric analysis of pulmonary deposition of aerosol particles inhaled via intratracheal nebulization, intratracheal instillation or nose-only inhalation in rats
Autor: C. P. Sabaitis, J. K. Coombs, B. K. J. Leong, D. A. Rop, C. S. Aaron
Publikováno v: Journal of Applied Toxicology. 18:149-160
The effectiveness of three techniques to deliver a diazo dye suspension into the lungs of rats was compared. The intratracheal nebulization (ITN) technique delivered 10 microl of the suspension per 5-ml puff of air in 10 puffs as an aerosol. The intr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7da4cf4f5645012696f482b4f09c8033
https://doi.org/10.1002/(sici)1099-1263(199803/04)18:2<149::aid-jat490>3.0.co
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3
Alterations in the cardiopulmonary effects and pharmacokinetics of a bisphosphonate drug by a cytochrome P-450 inhibitor in conscious rats
Autor: M. M. Cooper, T. W. Petry, P. Jeffrey, R. A. Jolly, D. A. Rop, T. J. Parker, C. P. Sabaitis, N. K. Burton, B. K. J. Leong
Publikováno v: Journal of Applied Toxicology. 17:279-288
U-91502, a bisphosphonate for arthritic inflammation treatment, was evaluated for its parental toxicity. The objective was to differentiate between the parent drug and a reactive metabolite(s) as the proximate cause of the toxic effects using two met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34da07fcf26e1b99ac3a9770d219ad37
https://doi.org/10.1002/(sici)1099-1263(199709)17:5<279::aid-jat438>3.0.co
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4
Quantitative morphometric analysis of pulmonary deposition of aerosol particles inhaled via intratracheal nebulization, intratracheal instillation or nose-only inhalation in rats
Autor: B K, Leong, J K, Coombs, C P, Sabaitis, D A, Rop, C S, Aaron
Publikováno v: Journal of applied toxicology : JAT. 18(2)
The effectiveness of three techniques to deliver a diazo dye suspension into the lungs of rats was compared. The intratracheal nebulization (ITN) technique delivered 10 microl of the suspension per 5-ml puff of air in 10 puffs as an aerosol. The intr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a87f979c15829cb30b2a359cf09c218a
https://pubmed.ncbi.nlm.nih.gov/9570698
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5
Alterations in the cardiopulmonary effects and pharmacokinetics of a bisphosphonate drug by a cytochrome P-450 inhibitor in conscious rats
Autor: B K, Leong, C P, Sabaitis, D A, Rop, P, Jeffrey, T J, Parker, N K, Burton, T W, Petry, R A, Jolly, M M, Cooper
Publikováno v: Journal of applied toxicology : JAT. 17(5)
U-91502, a bisphosphonate for arthritic inflammation treatment, was evaluated for its parental toxicity. The objective was to differentiate between the parent drug and a reactive metabolite(s) as the proximate cause of the toxic effects using two met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25d580f6b955355702a95286d641e243
https://pubmed.ncbi.nlm.nih.gov/9339740
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7
Retinopathy from inhaling 4,4?-methylenedianiline aerosols*1, *2
Autor: Royal J. Weaver, C. P. Sabaitis, J. A. Groehn, J. E. Lund, J. K. Coombs, B. K. J. Leong, R. L. Griffin
Publikováno v: Fundamental and Applied Toxicology. 9:645-658
4,4′-Methylenedianiline (MDA) is an important chemical intermediate in the production of isocyanates and polyurethane elastomers and polymers. The health hazards from acute inhalation exposure to the aerosols were evaluated. Guinea pigs of albino a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::588c1742fc4072449d8405a476f7400d
https://doi.org/10.1016/0272-0590(87)90171-0
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8
Retinopathy from inhaling 4,4'-methylenedianiline aerosols
Autor: B K, Leong, J E, Lund, J A, Groehn, J K, Coombs, C P, Sabaitis, R J, Weaver, R L, Griffin
Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 9(4)
4,4'-Methylenedianiline (MDA) is an important chemical intermediate in the production of isocyanates and polyurethane elastomers and polymers. The health hazards from acute inhalation exposure to the aerosols were evaluated. Guinea pigs of albino and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::668b91c98bb2111b61d2297bad1a9689
https://pubmed.ncbi.nlm.nih.gov/3692021
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10
Akademický článek
CD11b and Intercellular Adhesion Molecule-1 Are Involved in Pulmonary Neutrophil Recruitment in Lipopolysaccharide-Induced Airway Disease.
Autor: Moreland, Jessica G., Fuhrman, Robert M., Pruessner, Jonathan A., Schwartz, David A.
Publikováno v: American Journal of Respiratory Cell & Molecular Biology; 2002, Vol. 27 Issue 4, p474-480, 7p, 1 Chart, 4 Graphs
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