Zobrazeno 1 - 10
of 10
pro vyhledávání: '"C P, DeCicco"'
Autor:
E. Schaumann, G. A. Molander, B. M. Trost, A. Fuerstner, E. M. Carreira, E. J. Thomas, Masakatsu Shibasaki, C. P. Decicco, J.-Q. Yu, G. Koch
Publikováno v:
Catalytic Transformations via C-H Activation: C-C, C-N, C-O, C-Hal, and C-B Bond Formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adcff58b1586abc51ec94ade9feed773
https://doi.org/10.1055/b-003-129295
https://doi.org/10.1055/b-003-129295
Autor:
B. M. Trost, C. P. Decicco, G. A. Molander, J.-Q. Yu, E. M. Carreira, G. Koch, A. Fuerstner, E. Schaumann, Masakatsu Shibasaki, E. J. Thomas
Publikováno v:
Science of Synthesis ISBN: 9783132404137
Catalytic Transformations via C-H Activation Vol. 2
Catalytic Transformations via C-H Activation Vol. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3502186ba410fa51405a389f966283c
https://doi.org/10.1055/b-004-129675
https://doi.org/10.1055/b-004-129675
Autor:
P H, Carter, P A, Scherle, J K, Muckelbauer, M E, Voss, R Q, Liu, L A, Thompson, A J, Tebben, K A, Solomon, Y C, Lo, Z, Li, P, Strzemienski, G, Yang, N, Falahatpisheh, M, Xu, Z, Wu, N A, Farrow, K, Ramnarayan, J, Wang, D, Rideout, V, Yalamoori, P, Domaille, D J, Underwood, J M, Trzaskos, S M, Friedman, R C, Newton, C P, Decicco, J A, Muckelbauer
Publikováno v:
Proceedings of the National Academy of Sciences. 98:11879-11884
The binding of tumor necrosis factor alpha (TNF-α) to the type-1 TNF receptor (TNFRc1) plays an important role in inflammation. Despite the clinical success of biologics (antibodies, soluble receptors) for treating TNF-based autoimmune conditions, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a3908e9a1c37930ac42fa8b42d12d9
https://doi.org/10.1073/pnas.211178398
https://doi.org/10.1073/pnas.211178398
Publikováno v:
The Journal of Immunology. 159:4524-4531
Human monocytes rapidly produce TNF-alpha following activation by bacterial LPS. The message for TNF-alpha encodes a 26-kDa protein that is proteolytically processed to the secreted 17-kDa form. Sequencing of the N terminus of the protein secreted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa3f606481913b30970ec4873a91707b
https://doi.org/10.4049/jimmunol.159.9.4524
https://doi.org/10.4049/jimmunol.159.9.4524
Publikováno v:
Annals of the rheumatic diseases. 60
Studies conducted over the past decade have demonstrated a central role for tumour necrosis factor alpha (TNFalpha) in inflammatory diseases. As a result of this work, a number of biological agents that neutralise the activity of this cytokine have e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04a4c96c43da678d40f0c413c2c9aa59
https://pubmed.ncbi.nlm.nih.gov/11890648
https://pubmed.ncbi.nlm.nih.gov/11890648
Autor:
W, Yao, Z R, Wasserman, M, Chao, G, Reddy, E, Shi, R Q, Liu, M B, Covington, E C, Arner, M A, Pratta, M, Tortorella, R L, Magolda, R, Newton, M, Qian, M D, Ribadeneira, D, Christ, R R, Wexler, C P, Decicco
Publikováno v:
Journal of medicinal chemistry. 44(21)
A pharmacophore model of the P1' site, specific for aggrecanase, was defined using the specificity studies of the matrix metalloproteinases and the similar biological activity of aggrecanase and MMP-8. Incorporation of the side chain of a tyrosine re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66b60bcb0ff1f67244f659e6c7b37881
https://pubmed.ncbi.nlm.nih.gov/11585439
https://pubmed.ncbi.nlm.nih.gov/11585439
Autor:
E S, Priestley, C P, Decicco
Publikováno v:
Organic letters. 2(20)
The previously unreported alpha,alpha-disubstituted 1-aminoboronate esters have potential utility in peptidomimetic design, particularly against serine protease targets. A concise synthesis of 1-aminocyclopropaneboronate pinanediol ester is reported,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9be02a00da3146189d4ea6deedfcfb04
https://pubmed.ncbi.nlm.nih.gov/11009354
https://pubmed.ncbi.nlm.nih.gov/11009354
Publikováno v:
Bioorganicmedicinal chemistry letters. 10(8)
Peptide-based alpha-ketoamides, alpha-ketoesters and alpha-diketones were designed, synthesized and evaluated against HCV NS3 protease. Alpha-ketoamides have the highest affinity among the three classes, with 8 being the most potent inhibitor with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd3b9380589160a9bd93523c0a284cf1
https://pubmed.ncbi.nlm.nih.gov/10782670
https://pubmed.ncbi.nlm.nih.gov/10782670
Publikováno v:
The Journal of biological chemistry. 274(10)
A method was developed for generating soluble, active "aggrecanase" in conditioned media from interleukin-1-stimulated bovine nasal cartilage cultures. Using bovine nasal cartilage conditioned media as a source of the aggrecanase enzyme, an enzymatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e90fb7abaa4b7305fda49e961b233c2
https://pubmed.ncbi.nlm.nih.gov/10037754
https://pubmed.ncbi.nlm.nih.gov/10037754
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(9)
Human monocytes rapidly produce TNF-alpha following activation by bacterial LPS. The message for TNF-alpha encodes a 26-kDa protein that is proteolytically processed to the secreted 17-kDa form. Sequencing of the N terminus of the protein secreted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f992ce9294e21ddd52e4afcf4fe31a07
https://pubmed.ncbi.nlm.nih.gov/9379053
https://pubmed.ncbi.nlm.nih.gov/9379053