Zobrazeno 1 - 10
of 55
pro vyhledávání: '"C P, Case"'
Autor:
Murilo E. Graton, Floor Spaans, Rose He, Paulami Chatterjee, Raven Kirschenman, Anita Quon, Tom J. Phillips, C. Patrick Case, Sandra T. Davidge
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Prenatal hypoxia, a common pregnancy complication, leads to impaired cardiovascular outcomes in the adult offspring. It results in impaired vasodilation in coronary and mesenteric arteries of the adult offspring, due to reduced ni
Externí odkaz:
https://doaj.org/article/ee031b73af094c88bc8fb18478194b8a
Autor:
Tom J. Phillips, Hannah Scott, David A. Menassa, Ashleigh L. Bignell, Aman Sood, Jude S. Morton, Takami Akagi, Koki Azuma, Mark F. Rogers, Catherine E. Gilmore, Gareth J. Inman, Simon Grant, Yealin Chung, Mais M. Aljunaidy, Christy-Lynn Cooke, Bruno R. Steinkraus, Andrew Pocklington, Angela Logan, Gavin P. Collett, Helena Kemp, Peter A. Holmans, Michael P. Murphy, Tudor A. Fulga, Andrew M. Coney, Mitsuru Akashi, Sandra T. Davidge, C. Patrick Case
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Some neuropsychiatric disease, including schizophrenia, may originate during prenatal development, following periods of gestational hypoxia and placental oxidative stress. Here we investigated if gestational hypoxia promotes damaging secreti
Externí odkaz:
https://doaj.org/article/b061c7fc2e2040a6b274efd65f22ba8a
Autor:
Esha Ganguly, Mais M. Aljunaidy, Raven Kirschenman, Floor Spaans, Jude S. Morton, Thomas E. J. Phillips, C. Patrick Case, Christy-Lynn M. Cooke, Sandra T. Davidge
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Pregnancy complications associated with chronic fetal hypoxia have been linked to the development of adult cardiovascular disease in the offspring. Prenatal hypoxia has been shown to increase placental oxidative stress and impair placental function i
Externí odkaz:
https://doaj.org/article/87788c841e1e430ab9314ed7060693a1
Autor:
Hannah Scott, Alessio Alfieri, Paula J. Brunton, Mark F. Rogers, C. P. Case, Thomas J. Phillips, V. Volpato, Ying Sze
Publikováno v:
Scott, H, Phillips, T, Sze, Y, Alfieri, A, Rogers, M, Volpato, V, Case, P & Brunton, P 2020, ' Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring’s brain and behavior ', Neurobiology of Stress, vol. 13, pp. 100281 . https://doi.org/10.1016/j.ynstr.2020.100281
Neurobiology of Stress
Neurobiology of Stress, Vol 13, Iss, Pp 100281-(2020)
Neurobiology of Stress
Neurobiology of Stress, Vol 13, Iss, Pp 100281-(2020)
Maternal exposure to stress during pregnancy is associated with an increased risk of psychiatric disorders in the offspring in later life. The mechanisms through which the effects of maternal stress are transmitted to the fetus are unclear, however t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01f590c3059b68cd4b50e5b3d5f6781
https://hdl.handle.net/20.500.11820/24806ff4-7485-4533-a4fb-1c874ef04b99
https://hdl.handle.net/20.500.11820/24806ff4-7485-4533-a4fb-1c874ef04b99
Autor:
Nicola Jones, Jonathan G. Hanley, Thomas J. Phillips, Sharon Sanderson, C. P. Case, Veronica H.L. Leinster, Katja Simon
Publikováno v:
Leinster, V H L, Phillips, T J, Jones, N, Sanderson, S, Simon, K, Hanley, J & Case, C P 2020, ' Cortical cells are altered by factors including bone morphogenetic protein released from a placental barrier model under altered oxygenation ', Neuronal Signaling, vol. 4, no. 1 . https://doi.org/10.1042/NS20190148
Neuronal Signaling
Neuronal Signaling
Episodes of hypoxia and hypoxia/reoxygenation during foetal development have been associated with increased risk of neurodevelopmental conditions presenting in later life. The mechanism for this is not understood; however, several authors have sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abb6f89f592da371fde1b01053d3071
https://doi.org/10.1042/ns20190148
https://doi.org/10.1042/ns20190148
Autor:
Hannah Scott, Ying Sze, Mark F. Rogers, Alessio Alfieri, Paula J. Brunton, C. P. Case, Thomas J. Phillips
Maternal exposure to social stress during pregnancy is associated with an increased risk of psychiatric disorders in the offspring in later life. However, the mechanism through which the effects of maternal stress are transmitted to the foetus is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8484d16bd869dcf71eec6ee934a9184
Publikováno v:
Advanced Drug Delivery Reviews. 74:95-103
Three-dimensional (3D) tissue constructs consisting of human cells have opened a new avenue for tissue engineering, pharmaceutical and pathophysiological applications, and have great potential to estimate the dynamic pharmacological effects of drug c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5005813b2e808d433264195f783c96a0
https://doi.org/10.1016/j.addr.2014.01.003
https://doi.org/10.1016/j.addr.2014.01.003
Autor:
Michael Devey, Lauren A. Hails, Ashraf Malhas, Stephen Mann, Sue Hawkins, Eileen Ingham, Vijay Krishna Raghunathan, Jon D. Lane, C. P. Case, David J. Vaux, Sean A. Davis, I.T.H. Chang
Publikováno v:
Biomaterials. 34:3559-3570
Patients with cobalt chrome (CoCr) metal-on-metal (MOM) implants may be exposed to a wide size range of metallic nanoparticles as a result of wear. In this study we have characterised the biological responses of human fibroblasts to two types of synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6dfda577fdf91af44e52a6ed1b9b562
https://doi.org/10.1016/j.biomaterials.2013.01.085
https://doi.org/10.1016/j.biomaterials.2013.01.085
Autor:
R. Singh, M.-S. Suleiman, Duncan M. Baird, Gloria Lopez-Castejon, Saif Salih, C. P. Case, Michael Parry, Andrew D. Dick, Maeve A. Caldwell, John D. Aplin, C. Abbott, Karen Forbes, Laureline Roger, Hua Lin, R. Keehan, M. D. Lewis, N. Williams, Jack Ham, Melissa Westwood, B. Hardiman, I. Papageorgiou, Roger B. Newson, Andrew D. Randall, William Howard Evans, Helen Swalwell, M. Berry, Lizeth Lacharme-Lora, Eileen Ingham, Lucy A. Crompton, Jian Liu, Anna Katharina Simon, Aman Sood, Danny S. Roh, Peter W. Andrews, Paul J. Gokhale, Elke Winterhager, Ruth Grümmer, Mark A. Birch-Machin, Red Garland
Publikováno v:
Nature Nanotechnology
Nature Nanotechnology, Nature Publishing Group, 2011, 6 (12), pp.824-833. ⟨10.1038/nnano.2011.188⟩
Nature Nanotechnology, 2011, 6 (12), pp.824-833. ⟨10.1038/nnano.2011.188⟩
Nature Nanotechnology, Nature Publishing Group, 2011, 6 (12), pp.824-833. ⟨10.1038/nnano.2011.188⟩
Nature Nanotechnology, 2011, 6 (12), pp.824-833. ⟨10.1038/nnano.2011.188⟩
The use of nanoparticles in medicine is ever increasing, and it is important to understand their targeted and non-targeted effects. We have previously shown that nanoparticles can cause DNA damage to cells cultured below a cellular barrier without cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260f9c3304e6dfd741be289ebb53ec96
https://ora.ox.ac.uk/objects/uuid:9a0712b6-9c91-49f0-864d-5547f640f77d
https://ora.ox.ac.uk/objects/uuid:9a0712b6-9c91-49f0-864d-5547f640f77d
Autor:
S T, Donell, C, Darrah, J F, Nolan, J, Wimhurst, A, Toms, T H W, Barker, C P, Case, J K, Tucker, R, Farrar
Publikováno v:
The Journal of Bone and Joint Surgery. British volume. :1501-1508
Metal-on-metal total hip replacement has been targeted at younger patients with anticipated long-term survival, but the effect of the production of metal ions is a concern because of their possible toxicity to cells. We have reviewed the results of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5114f1726bf91b50e5bd2d176d321acd
https://doi.org/10.1302/0301-620x.92b11.24504
https://doi.org/10.1302/0301-620x.92b11.24504