Výsledky vyhledávání - "C P, Briscoe"

Fatty acids inhibit leptin signalling in BRIN-BD11 insulinoma cells

Autor: C P, Briscoe, S, Hanif, J R, Arch, M, Tadayyon

Publikováno v: Journal of Molecular Endocrinology. 26:145-154

The effect of treatment with a 0.03% fatty acid (FA) cocktail on leptin-receptor-mediated STAT (signal transducers and activators of transcription) activation in the rat insulinoma cell line BRIN-BD11 was investigated. Leptin (10 nM) stimulated the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7468f6f13d1861462e1526af6141b71a
https://doi.org/10.1677/jme.0.0260145

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Energy restriction enhances therapeutic efficacy of the PPARgamma agonist, rosiglitazone, through regulation of visceral fat gene expression

Autor: C. P. Briscoe, Gary B.T. Moore, R. E. Buckingham, John P.H. Wilding, John C. Clapham, Lucy Pickavance

Publikováno v: Diabetes, obesitymetabolism. 10(3)

Aim: Consumption of a palatable diet can induce hyperphagia, leading to weight gain (dietary obesity) and insulin resistance in rats. Thiazolidinediones (TZDs) can also induce hyperphagia in rats but conversely have an insulin-sensitizing effect. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0460777844eb641648c1639d05976b
https://pubmed.ncbi.nlm.nih.gov/18269641

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The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts

Autor: C P Briscoe, Michael J. Cross, Michael J.O. Wakelam, A Martin

Publikováno v: The Biochemical journal. 306

The regulation of bombesin-stimulated phospholipase D (PLD) activity in Swiss 3T3 fibroblasts was examined. Increasing protein-tyrosine phosphorylation by using pervanadate to inhibit tyrosine phosphatases was found to stimulate protein kinase C (PKC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1365e22eece00135b2f26d8d63177740
https://pubmed.ncbi.nlm.nih.gov/7864797

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Phosphatidylcholine hydrolysis: a multiple messenger generating system

Autor: M J, Wakelam, T R, Pettitt, P, Kaur, C P, Briscoe, A, Stewart, A, Paul, A, Paterson, M J, Cross, S D, Gardner, S, Currie

Publikováno v: Advances in second messenger and phosphoprotein research. 28

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e021e09751194b00dd241d4daee5af95
https://pubmed.ncbi.nlm.nih.gov/8398420

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