Identification of functional domains in murine granulocyte-macrophage colony-stimulating factor using monoclonal antibodies to synthetic peptides

Autor: R S Greenfield, G R Braslawsky, K F Kadow, G L Spitalny, D Chace, C O Bull, I Bursuker

Publikováno v: The Journal of Immunology. 150:5241-5251

Granulocyte-macrophage (GM)-CSF is an important hematopoietic cytokine that regulates proliferation and differentiation of macrophages, neutrophils, and eosinophils. In this study, we generated mAb to five synthetic peptides that correspond to region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3d40ebdd5d87f9ca08405bb97549cae
https://doi.org/10.4049/jimmunol.150.12.5241

Insights into the Conformational Plasticity of the Protein Kinase Akt1 by Multi‐Lateral Dipolar Spectroscopy.

Autor: Stehle, Juliane¹ (AUTHOR), Weisner, Jörn² (AUTHOR), Eichhorn, Leanne¹ (AUTHOR), Rauh, Daniel² (AUTHOR) daniel.rauh@tu-dortmund.de, Drescher, Malte¹ (AUTHOR) malte.drescher@uni-konstanz.de

Publikováno v: Chemistry - A European Journal. 4/25/2023, Vol. 29 Issue 24, p1-7. 7p.

NEW IMIDAZO[4,5-B]PYRIDINE DERIVATIVES: SYNTHESIS, CRYSTAL STRUCTURES, HIRSHFELD SURFACE ANALYSIS, DFT COMPUTATIONS AND MONTE CARLO SIMULATIONS.

Autor: Jabri, Zainab¹, El Ibrahimi, Brahim^2,3, Jarmoni, Karim¹, Sabir, Safia¹, Misbahi, Khalid¹, Rodi, Youssef Kandri¹, Mashrai, Ashraf⁴, Hökelek, Tuncer⁵, Mague, Joel T.⁶, Sebbar, Nada Kheira^3,7,8 snounousebbar@gmail.com, Essassi, El Mokhtar⁸

Publikováno v: Journal of Chemical Technology & Metallurgy. 2022, Vol. 57 Issue 3, p451-463. 13p.

Synthetic Benzylic Diselenides and Disulfides: Potential Anticancer Activities via Modulation of the ROS-Dependent Akt/β-Catenin Signaling Pathway.

Autor: Barman P; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India., Misra R; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India., Pal N; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India., Sarkar S; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India., Bhabak KP; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India.

Publikováno v: ChemMedChem [ChemMedChem] 2024 Nov 18; Vol. 19 (22), pp. e202400358. Date of Electronic Publication: 2024 Sep 21.

Allosterische Kinaseinhibitoren – Erwartungen und Chancen.

Autor: Lu, Xiaoyun¹ (AUTHOR) luxy2016@jnu.edu.cn, Smaill, Jeff B.² (AUTHOR), Ding, Ke¹ (AUTHOR) dingke@jnu.edu.cn

Publikováno v: Angewandte Chemie. 8/10/2020, Vol. 132 Issue 33, p13868-13881. 14p.