Zobrazeno 1 - 10
of 38
pro vyhledávání: '"C O, Tacket"'
Autor:
Genevieve Losonsky, Jane Michalski, Myron M. Levine, James P. Nataro, Robert R. Edelman, K. L. Kotloff, C O Tacket, J B Kaper
Publikováno v:
Scopus-Elsevier
A live oral cholera vaccine should ideally protect against both classical and El Tor biotypes of Vibrio cholerae 01. An El Tor biotype vaccine strain, therefore, would complement classical cholera vaccine strain CVD 103-HgR, a strain already in use i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409d2b0bb0c6c735895e465e69b6cfd2
https://doi.org/10.4269/ajtmh.1997.56.533
https://doi.org/10.4269/ajtmh.1997.56.533
Autor:
Judith A. Johnson, Jr Jg Morris, James B. Kaper, Myron M. Levine, C O Tacket, Genevieve Losonsky, Yu Lim, Laurie E. Comstock, P Motamedi
Publikováno v:
Scopus-Elsevier
The emergence of a new agent of cholera, Vibrio cholerae O139, has prompted a reevaluation of the vibriocidal antibody assay. This assay, primarily directed to lipopolysaccharide, is an important correlate of O1 immunity. V. cholerae O139 strains are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd07196fa8c3d0475967922c2cfc380
https://doi.org/10.1128/cdli.4.3.264-269.1997
https://doi.org/10.1128/cdli.4.3.264-269.1997
Autor:
Elizabeth Nardin, Myron M. Levine, Fernando R. Noriega, Marcelo B. Sztein, Genevieve Losonsky, David M. Hone, Armando Isibasi, C. Gonzalez, T. R. Fouts, James P. Nataro, A. Malik, Stephen L. Hoffman, Jonathan R. Davis, C O Tacket, D. G. Heppner
Publikováno v:
Journal of Infectious Diseases. 169:927-931
rcsp, encoding amino acids 21-398 of Plasmodium falciparum circumsporozoite protein (CSP), under control of tacP was integrated into the chromosomal delta aroC locus of attenuated delta aroC, delta aroD Salmonella typhi CVD 908. By immunoblot and ELI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66f7bc6770ada0ee31df26bb1655e7c
https://doi.org/10.1093/infdis/169.4.927
https://doi.org/10.1093/infdis/169.4.927
Autor:
Myron M. Levine, Genevieve Losonsky, Steven S. Wasserman, Michael S. Donnenberg, C O Tacket, Stephen P. James, James P. Nataro, J B Kaper
Publikováno v:
Journal of Clinical Investigation. 92:1412-1417
Enteropathogenic Escherichia coli (EPEC) infections are a leading cause of infant diarrhea in developing countries. Recently eaeA, a gene necessary for the characteristic intimate attachment of EPEC to epithelial cells in tissue culture, was describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::115fb5ca82d968c173bebda11f298a31
https://doi.org/10.1172/jci116717
https://doi.org/10.1172/jci116717
Publikováno v:
Scopus-Elsevier
Peripheral blood immunoglobulin A antibody-secreting-cell (ASC) responses are thought to reflect the mucosal immune response to locally presented antigens. We evaluated the ASC response to cholera toxin (CT) and Inaba lipopolysaccharide (LPS) in 26 N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddaf7253b511b6ad8ef0f3992d9808f1
https://doi.org/10.1128/iai.61.2.729-733.1993
https://doi.org/10.1128/iai.61.2.729-733.1993
Autor:
David M. Hone, Myron M. Levine, C O Tacket, Andrea M. Harris, Genevieve Losonsky, Bradford A. Kay
Publikováno v:
Journal of Clinical Investigation. 90:412-420
Candidate vector vaccine strain CVD 906 (aroC- and aroD- derivative of virulent Salmonella typhi strain ISP1820) was evaluated in phase 1 clinical trials. The first nine volunteers ingested a single dose of 5 x 10(7) CVD 906 bacilli. At this dose CVD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073899e40719f6db703059bbd1ad3772
https://doi.org/10.1172/jci115876
https://doi.org/10.1172/jci115876
Autor:
Robert R. Edelman, Andrea M. Harris, rd R Curtiss, Linda Guers, C O Tacket, Myron M. Levine, David M. Hone, Genevieve Losonsky, S. M. Kelly
Publikováno v:
Infection and Immunity. 60:536-541
Three attenuated Salmonella typhi strains have been constructed by introducing deletions in aroC and aroD or deletions in cya and crp into one of two wild-type parent strains, Ty2 or ISP1820. These mutant strains were designated CVD 906 (ISP1820 delt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7060ce4086740295a4440e8f85817d70
https://doi.org/10.1128/iai.60.2.536-541.1992
https://doi.org/10.1128/iai.60.2.536-541.1992
Autor:
C. O. Tacket
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783540708575
Vaccines consisting of transgenic plant-derived antigens offer a new strategy for development of safe, inexpensive vaccines. The vaccine antigens can be eaten with the edible part of the plant or purified from plant material. In phase 1 clinical stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaccc65f328bbb0b7f145a56ad733e72
https://doi.org/10.1007/978-3-540-70868-1_6
https://doi.org/10.1007/978-3-540-70868-1_6
Publikováno v:
Research in Microbiology. 141:807-816
In recent years there has been a resurgence of research to develop new and improved attenuated strains of Salmonella typhi to function as live oral vaccines against typhoid fever and to serve as “carrier” vaccines to express foreign antigens of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6d16580af8fab101382a05d3fa9085
https://doi.org/10.1016/0923-2508(90)90114-6
https://doi.org/10.1016/0923-2508(90)90114-6
Autor:
C O Tacket, J B Kaper, Richard L. Guerrant, R Edelman, M A Schleupner, Theodore S. Steiner, T M Silva
Publikováno v:
Infection and Immunity. 64:2362-2364
Using a lactoferrin latex agglutination assay, we have compared the inflammatory responses to a cholera vaccine candidate, CVD 110, in which all known toxin genes have been deleted or mutated yet still produced significant diarrhea, with a less react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e234fd070df488a3804e2c1ba0b25fc
https://doi.org/10.1128/iai.64.6.2362-2364.1996
https://doi.org/10.1128/iai.64.6.2362-2364.1996