Zobrazeno 1 - 10
of 20
pro vyhledávání: '"C O, Jacob"'
Publikováno v:
The Journal of Immunology. 156:3043-3050
Lupus-prone mice show reduced production of TNF-alpha and, upon long-term treatment with recombinant TNF-alpha, significant protection from disease development. Mutational analysis of the 5'-untranslated region (UTR) and 3'-UTR of the mouse TNF-alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb0275235d4559b6060ad3400980874
https://doi.org/10.4049/jimmunol.156.8.3043
https://doi.org/10.4049/jimmunol.156.8.3043
Publikováno v:
The Journal of Immunology. 155:4909-4916
We have recently shown that PGE2 inhibits the release of TNF-alpha from LPS-stimulated murine peritoneal macrophages via a feedback mechanism involving IL-10. Here we demonstrate that a rolipram-sensitive phosphodiesterase (PDE) type IV participates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec941430a96b00831238dac78d8f7e1
https://doi.org/10.4049/jimmunol.155.10.4909
https://doi.org/10.4049/jimmunol.155.10.4909
Publikováno v:
The Journal of Immunology. 148:3674-3678
In a recent report we showed that IL-6 is an important mediator of experimental cancer cachexia in the colon-26 (C-26) tumor system. In culture, on a per cell basis, C-26.IVX cell line (which develops tumors and induces severe cachexia of syngeneic h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1272b5b9d26c7f5fddf1507f4a5349be
https://doi.org/10.4049/jimmunol.148.11.3674
https://doi.org/10.4049/jimmunol.148.11.3674
Publikováno v:
The Journal of Experimental Medicine
Murine resistance to development of toxoplasmic encephalitis (TE) has recently been mapped to the D region of the major histocompatibility complex (H-2). Since the gene for tumor necrosis factor alpha (TNF-alpha) is located 5' of the D region and TNF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35155c2a0ec55b832172f4911e859d9b
https://doi.org/10.1084/jem.175.3.683
https://doi.org/10.1084/jem.175.3.683
Autor:
Y Watanabe, C O Jacob
Publikováno v:
The Journal of Immunology. 146:899-905
MHC class II induction by cytokines has been suggested to play a major role in the initiation and propagation of immune and autoimmune processes. TNF-alpha has been found both to enhance and also to inhibit IFN-gamma-induced MHC class II expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e9fe21f24033abecef892d0877a7c7
https://doi.org/10.4049/jimmunol.146.3.899
https://doi.org/10.4049/jimmunol.146.3.899
Autor:
R, Mehrian, F P, Quismorio, G, Strassmann, M M, Stimmler, D A, Horwitz, R C, Kitridou, W J, Gauderman, J, Morrison, C, Brautbar, C O, Jacob
Publikováno v:
Arthritis and rheumatism. 41(4)
To determine whether genes participating in programmed cell death, including bcl-2, IL-10, Fas-L, and CTLA-4, may contribute to the genetic predisposition to systemic lupus erythematosus (SLE).First, intragenic markers for the bcl-2, IL-10, Fas-L, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b60d1868a9f5f8a15b4a1f331324863
https://pubmed.ncbi.nlm.nih.gov/9550468
https://pubmed.ncbi.nlm.nih.gov/9550468
Publikováno v:
Arthritis and rheumatism. 40(6)
To determine the cytolytic effector pathway involved in impaired generation of nonrestricted cytolytic activity in systemic lupus erythematosus (SLE).Peripheral blood mononuclear cells (PBMC) from normal subjects and SLE patients were stimulated in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::034a90546f2140425f24edaba6ca4650
https://pubmed.ncbi.nlm.nih.gov/9182924
https://pubmed.ncbi.nlm.nih.gov/9182924
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(8)
Lupus-prone mice show reduced production of TNF-alpha and, upon long-term treatment with recombinant TNF-alpha, significant protection from disease development. Mutational analysis of the 5'-untranslated region (UTR) and 3'-UTR of the mouse TNF-alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::740461bfcb885e6682c1a14cc5f31907
https://pubmed.ncbi.nlm.nih.gov/8609427
https://pubmed.ncbi.nlm.nih.gov/8609427
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(10)
We have recently shown that PGE2 inhibits the release of TNF-alpha from LPS-stimulated murine peritoneal macrophages via a feedback mechanism involving IL-10. Here we demonstrate that a rolipram-sensitive phosphodiesterase (PDE) type IV participates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbe249904191ba2fd1c69534171b2f0e
https://pubmed.ncbi.nlm.nih.gov/7594495
https://pubmed.ncbi.nlm.nih.gov/7594495
Autor:
C O, Jacob
Publikováno v:
Regional immunology. 4(5)
Rather than being involved merely in the effector arm of inflammatory processes that contribute to autoimmune organ destruction, a primary involvement of TNF may be in some of the more basic mechanisms that occur in autoimmune disease. In this review
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8739a1173d411f2dcac7b52bff2d02fc
https://pubmed.ncbi.nlm.nih.gov/1290749
https://pubmed.ncbi.nlm.nih.gov/1290749