Zobrazeno 1 - 10
of 2 825
pro vyhledávání: '"C Nichols"'
Autor:
Samantha Muscat, Anne E. C. Nichols
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Tendon injuries disrupt successful transmission of force between muscle and bone, resulting in reduced mobility, increased pain, and significantly reduced quality of life for affected patients. There are currently no targeted treatments to improve te
Externí odkaz:
https://doaj.org/article/9ebf9e618ae5471fa917c8f6cad188fb
Autor:
Alexander Bontempo, Alexandra Chirino, Alireza Heidari, Alexandra Lugo, Satoru Shindo, Maria R. Pastore, Riccardo Madonia, Sibel A. Antonson, Cristina Godoy, Frank C. Nichols, Jan Potempa, Mary Ellen Davey, Toshihisa Kawai, Mark J. Cayabyab
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT The COVID-19 pandemic persists despite the availability of vaccines, and it is, therefore, crucial to develop new therapeutic and preventive approaches. In this study, we investigated the potential role of oral microbiome in SARS-CoV-2 infec
Externí odkaz:
https://doaj.org/article/ca9be7f51c8d413ea79582e6281a76ce
Autor:
Li Gao, John Skinner, Tanmay Nath, Qing Lin, Megan Griffiths, Rachel L. Damico, Michael W. Pauciulo, William C. Nichols, Paul M. Hassoun, Allen D. Everett, Roger A. Johns
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Abnormal remodeling of distal pulmonary arteries in patients with pulmonary arterial hypertension (PAH) leads to progressively increased pulmonary vascular resistance, followed by right ventricular hypertrophy and failure. Despite
Externí odkaz:
https://doaj.org/article/6ca03ee34a4e496ca26a6aba6d9e3633
Autor:
Benedek Dankó, Julia Hess, Kristian Unger, Daniel Samaga, Christoph Walz, Axel Walch, Na Sun, Philipp Baumeister, Peter Y. F. Zeng, Franziska Walter, Sebastian Marschner, Richard Späth, Olivier Gires, Timm Herkommer, Ramin Dazeh, Thaina Matos, Lisa Kreutzer, Johann Matschke, Katharina Eul, Frederick Klauschen, Ulrike Pflugradt, Martin Canis, Ute Ganswindt, Joe S. Mymryk, Barbara Wollenberg, Anthony C. Nichols, Claus Belka, Horst Zitzelsberger, Kirsten Lauber, Martin Selmansberger
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-20 (2024)
Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous malignancy that remains a significant challenge in clinical management due to frequent treatment failures and pronounced therapy resistance. While metabolic dysregulation appea
Externí odkaz:
https://doaj.org/article/478152ef0db84845b323352406d212bd
Autor:
Sahar A. Saddoughi, MD, PhD, Chelsea Powell, MD, Gregory R. Stroh, MD, Srinivasan Rajagopalan, PhD, Brian J. Bartholmai, MD, Jennifer M. Boland, MD, Marie Christine Aubry, MD, William S. Harmsen, MS, Shanda H. Blackmon, MD, MPH, Stephen D. Cassivi, MD, Francis C. Nichols, MD, Janani S. Reisenauer, MD, K. Robert Shen, MD, Aaron S. Mansfield, MD, Fabien Maldonado, MD, Tobias Peikert, MD, Dennis A. Wigle, MD, PhD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 1, Pp 44-52 (2024)
Objective: To investigate whether an artificial intelligence (AI)–based model can predict tumor invasiveness in patients with multifocal lung adenocarcinoma (MFLA). Patients and Methods: Patients with MFLA who underwent surgical resection were enro
Externí odkaz:
https://doaj.org/article/7f005bdf4a234beabb353292c8eae05d
Autor:
Shirin Ghods, Artur Muszyński, Hyojik Yang, Ratnam S. Seelan, Asal Mohammadi, Jacob S. Hilson, Griffin Keiser, Frank C. Nichols, Parastoo Azadi, Robert K. Ernst, Fata Moradali
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundThis study unveils the intricate functional association between cyclic di-3’,5’-adenylic acid (c-di-AMP) signaling, cellular bioenergetics, and the regulation of lipopolysaccharide (LPS) profile in Porphyromonas gingivalis, a Gram-negat
Externí odkaz:
https://doaj.org/article/1015e19a0cc64c33918977091768a1d6
Autor:
Arun Jose, Jean M. Elwing, Steven M. Kawut, Michael W. Pauciulo, Kenneth E. Sherman, William C. Nichols, Michael B. Fallon, Francis X. McCormack
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Portopulmonary hypertension (PoPH) is a type of pulmonary vascular disease due to portal hypertension that exhibits high morbidity and mortality. The mechanisms driving disease are unknown, and transcriptional characteristics unique to the P
Externí odkaz:
https://doaj.org/article/3f66553713d04b82baf7ae63a140a0fa
Autor:
Theodore C. Nichols, Lisa A. Clark
Publikováno v:
Wildlife Society Bulletin, Vol 48, Iss 1, Pp n/a-n/a (2024)
Abstract Mute swans (Cygnus olor) have increased in New Jersey at ~7%/yr since the mid‐1980s with the population peaking at 1,890 mute swans by 2005. Wildlife agencies have implemented management programs to reduce mute swan numbers to population o
Externí odkaz:
https://doaj.org/article/01a97c85013e4504b1d08bf783127fbc
Autor:
Peter Y.F. Zeng, Stephenie D. Prokopec, Stephen Y. Lai, Nicole Pinto, Michelle A. Chan-Seng-Yue, Roderick Clifton-Bligh, Michelle D. Williams, Christopher J. Howlett, Paul Plantinga, Matthew J. Cecchini, Alfred K. Lam, Iram Siddiqui, Jianxin Wang, Ren X. Sun, John D. Watson, Reju Korah, Tobias Carling, Nishant Agrawal, Nicole Cipriani, Douglas Ball, Barry Nelkin, Lisa M. Rooper, Justin A. Bishop, Cathie Garnis, Ken Berean, Norman G. Nicolson, Paul Weinberger, Ying C. Henderson, Christopher M. Lalansingh, Mao Tian, Takafumi N. Yamaguchi, Julie Livingstone, Adriana Salcedo, Krupal Patel, Frederick Vizeacoumar, Alessandro Datti, Liu Xi, Yuri E. Nikiforov, Robert Smallridge, John A. Copland, Laura A. Marlow, Martin D. Hyrcza, Leigh Delbridge, Stan Sidhu, Mark Sywak, Bruce Robinson, Kevin Fung, Farhad Ghasemi, Keith Kwan, S. Danielle MacNeil, Adrian Mendez, David A. Palma, Mohammed I. Khan, Mushfiq Shaikh, Kara M. Ruicci, Bret Wehrli, Eric Winquist, John Yoo, Joe S. Mymryk, James W. Rocco, David Wheeler, Steve Scherer, Thomas J. Giordano, John W. Barrett, William C. Faquin, Anthony J. Gill, Gary Clayman, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113826- (2024)
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid
Externí odkaz:
https://doaj.org/article/c5a6abf2e7ba48ce977235cab50cb266
Autor:
Bhavya S. Doshi, Benjamin J. Samelson-Jones, Timothy C. Nichols, Elizabeth P. Merricks, Joshua L. Siner, Robert A. French, Ben J. Lee, Valder R. Arruda, Mary Beth Callan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101205- (2024)
The hemophilias are the most common severe inherited bleeding disorders and are caused by deficiency of clotting factor (F) VIII (hemophilia A) or FIX (hemophilia B). The resultant bleeding predisposition significantly increases morbidity and mortali
Externí odkaz:
https://doaj.org/article/b7c59031eecd4b9ca3b2c7a6fcb6f7d7