Zobrazeno 1 - 10
of 57
pro vyhledávání: '"C N Serhan"'
Autor:
C. N. Serhan
Publikováno v:
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents. 1:177-192
Publikováno v:
The Journal of Immunology. 157:2149-2154
Lipoxins are bioactive eicosanoids that are generated during multicellular events such as inflammation, thrombosis, and atherosclerosis. They have selective actions on peripheral blood cells, in that previous results indicate that lipoxin A4 (LXA4) a
Publikováno v:
The Journal of Immunology. 156:2264-2272
Lipoxins are bioactive eicosanoids that are generated within the vascular lumen by leukocytes and transcellular biosynthetic routes during multicellular responses. Polymorphomuclear neutrophils (PMN) and endothelial cells express high affinity recept
Publikováno v:
ChemInform. 22
Autor:
L V, Norling, C N, Serhan
Publikováno v:
Journal of internal medicine. 268(1)
A highly orchestrated inflammatory response and its completion, termed resolution, are essential for ongoing health. Thus, complete understanding of the cellular and molecular events that govern natural resolution is vital. Using an unbiased systems
Publikováno v:
British journal of pharmacology. 158(4)
Inflammation is associated with oxidative stress and local generation of lipid peroxidation-derived aldehydes, such as 4-hydroxy-trans-2-nonenal (HNE). In most tissues, HNE is readily conjugated with glutathione and presently it is unknown whether gl
Autor:
B S, Herrera, T, Ohira, L, Gao, K, Omori, R, Yang, M, Zhu, M N, Muscara, C N, Serhan, T E, Van Dyke, R, Gyurko
Publikováno v:
British journal of pharmacology. 155(8)
The inflammation-resolving lipid mediator resolvin E1 (RvE1) effectively stops inflammation-induced bone loss in vivo in experimental periodontitis. It was of interest to determine whether RvE1 has direct actions on osteoclast (OC) development and bo
Autor:
C N, Serhan, N, Chiang
Publikováno v:
British journal of pharmacology. 153
Complete resolution of an acute inflammatory response and its return to homeostasis are essential for healthy tissues. Here, we overview ongoing efforts to characterize cellular and molecular mechanisms that govern the resolution of self-limited infl
Autor:
C N, Serhan
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 49(3)
Eicosanoids are known to play important roles in cell-cell communications and as intracellular signals that are critical components of multi-cellular responses such as acute inflammation and reperfusion injury. Recent findings have given rise to seve
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 51(4 Pt 1)
Aspirin therapy inhibits prostaglandin biosynthesis; yet via acetylation of cyclooxygenase 2 (COX-2) it leads to bioactive lipoxins epimeric at carbon 15 (15-epi-LX, also termed aspirin-triggered lipoxin or ATL). Here, we review our findings indicati