Zobrazeno 1 - 10
of 28
pro vyhledávání: '"C N Robson"'
Publikováno v:
Molecular and Cellular Biology. 13:5370-5376
The DNA binding activity of the c-jun proto-oncogene product is inhibited by oxidation of a specific cysteine residue (Cys-252) in the DNA binding domain. Jun protein inactivated by oxidation of this residue can be efficiently reactivated by a factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02437729e94196d70865a9ed333c5859
https://doi.org/10.1128/mcb.13.9.5370-5376.1993
https://doi.org/10.1128/mcb.13.9.5370-5376.1993
Publikováno v:
Nucleic Acids Research. 20:4417-4421
Apurinic/apyrimidinic (AP) sites are pre-mutagenic DNA lesions which occur spontaneously and following exposure of cells to ionising radiation or chemical mutagens. HAP1 (Human AP endonuclease 1), the major enzyme in human cells initiating repair of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ae460f727d41ef0509b788b86f84c1
https://doi.org/10.1093/nar/20.17.4417
https://doi.org/10.1093/nar/20.17.4417
Publikováno v:
The Journal of pathology. 215(1)
The RNA-binding protein Sam68 has been reported to be up-regulated in clinical cases of prostate cancer (PCa), where it is thought to contribute to cell proliferation and survival. Consistent with this, we observed over-expression of Sam68 in a panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0f2eeb4afd88c929c977729fffd9d45
https://pubmed.ncbi.nlm.nih.gov/18273831
https://pubmed.ncbi.nlm.nih.gov/18273831
Publikováno v:
The Journal of pathology. 214(3)
Bone morphogenetic protein-6 (BMP-6) has been strongly implicated in prostate cancer development and bone metastasis. Our previous data showed that BMP-6 mRNA was absent in patients with benign prostatic hyperplasia, but evident in primary tumours wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ab32f46323d22c52f390c2dad611c4a
https://pubmed.ncbi.nlm.nih.gov/18072288
https://pubmed.ncbi.nlm.nih.gov/18072288
Publikováno v:
The Journal of urology. 165(5)
After transposition into the urinary tract, intestinal segments continue to produce mucus. We determine the effectiveness of muco-regulatory drugs, including N-acetylcysteine, aspirin and ranitidine, in reducing mucus secretion and urine viscosity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14644131c9cabc45988eada59f74a579
https://pubmed.ncbi.nlm.nih.gov/11342892
https://pubmed.ncbi.nlm.nih.gov/11342892
Publikováno v:
BJU international. 86(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08b3f08914db028bf817766c52d4c2eb
https://pubmed.ncbi.nlm.nih.gov/11119093
https://pubmed.ncbi.nlm.nih.gov/11119093
Publikováno v:
BJU international. 86(6)
To determine the effect of insulin-like growth factor (IGF)-II on androgen receptor (AR) expression in prostate tissue, as IGFs may be important in re-activating androgen-regulated genes in advanced prostate cancer because they can trans-activate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f26dc0d5a710928c5ad7d8d80ca6e4d1
https://pubmed.ncbi.nlm.nih.gov/11069386
https://pubmed.ncbi.nlm.nih.gov/11069386
Publikováno v:
BJU international. 86(6)
To assess whether mutations in the hot-spots of the fibroblast growth factor (FGF) receptor-2 gene (FGFR2, exons encoding the IIIa, IIIb, IIIc and transmembrane domain, TMD) are associated with the development of prostate cancer, as the IIIb variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15f92e892ee8dc3a392631dbe698e5b5
https://pubmed.ncbi.nlm.nih.gov/11069376
https://pubmed.ncbi.nlm.nih.gov/11069376
Publikováno v:
The Journal of urology. 164(6)
Keratinocyte growth factor (KGF) is a stromally derived growth factor important in mediating androgen induced activities in benign prostatic hyperplasia (BPH) and prostate cancer. We assessed whether serum KGF could be used as a molecular marker in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1791df3042c507ddd62794598f772eaf
https://pubmed.ncbi.nlm.nih.gov/11061946
https://pubmed.ncbi.nlm.nih.gov/11061946
Publikováno v:
The Journal of urology. 164(4)
The repertoire of mucin (MUC) gene expression in the normal human urothelium is poorly defined and the alterations in MUC gene expression following transposition of intestinal segments into the urinary tract has not previously been studied. The aims
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e9cb29684a4ddc27ea21867d0c1d511
https://pubmed.ncbi.nlm.nih.gov/11435871
https://pubmed.ncbi.nlm.nih.gov/11435871