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of 271
pro vyhledávání: '"C N Robson"'
Autor:
Aragona, F, Calabria, S, Bellinghieri, Guido, Pecchini, F, Conte, F, Chiappini, Mg, Ferrannini, M, Lagona, C, Mallamace, Agostino, Manni, M, Diluca, M, Sardella, D, Taggi, F.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3978::9f19e4acc9ff77b3c91c1872a60f5e26
http://hdl.handle.net/11570/1892165
http://hdl.handle.net/11570/1892165
Akademický článek
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Publikováno v:
Molecular and Cellular Biology. 13:5370-5376
The DNA binding activity of the c-jun proto-oncogene product is inhibited by oxidation of a specific cysteine residue (Cys-252) in the DNA binding domain. Jun protein inactivated by oxidation of this residue can be efficiently reactivated by a factor
Publikováno v:
Nucleic Acids Research. 20:4417-4421
Apurinic/apyrimidinic (AP) sites are pre-mutagenic DNA lesions which occur spontaneously and following exposure of cells to ionising radiation or chemical mutagens. HAP1 (Human AP endonuclease 1), the major enzyme in human cells initiating repair of
Publikováno v:
The Journal of pathology. 215(1)
The RNA-binding protein Sam68 has been reported to be up-regulated in clinical cases of prostate cancer (PCa), where it is thought to contribute to cell proliferation and survival. Consistent with this, we observed over-expression of Sam68 in a panel
Publikováno v:
The Journal of pathology. 214(3)
Bone morphogenetic protein-6 (BMP-6) has been strongly implicated in prostate cancer development and bone metastasis. Our previous data showed that BMP-6 mRNA was absent in patients with benign prostatic hyperplasia, but evident in primary tumours wi
Publikováno v:
The Journal of urology. 165(5)
After transposition into the urinary tract, intestinal segments continue to produce mucus. We determine the effectiveness of muco-regulatory drugs, including N-acetylcysteine, aspirin and ranitidine, in reducing mucus secretion and urine viscosity in
Publikováno v:
BJU international. 86(9)
Publikováno v:
BJU international. 86(6)
To determine the effect of insulin-like growth factor (IGF)-II on androgen receptor (AR) expression in prostate tissue, as IGFs may be important in re-activating androgen-regulated genes in advanced prostate cancer because they can trans-activate the
Publikováno v:
BJU international. 86(6)
To assess whether mutations in the hot-spots of the fibroblast growth factor (FGF) receptor-2 gene (FGFR2, exons encoding the IIIa, IIIb, IIIc and transmembrane domain, TMD) are associated with the development of prostate cancer, as the IIIb variant