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pro vyhledávání: '"C N Gorini"'
Autor:
C Garbino, Gilberto Schwartsmann, D. R. A. Mans, Holger J. Schünemann, C N Gorini, A F Filho, Luciane Pons DiLeone, G Sabini, I Muse
Publikováno v:
Investigational new drugs. 18(1)
The authors describe a phase I trial of cisplatin plus decitabine, a novel DNA-hypomethylating agent, in patients with advanced solid tumors, which was followed by an early phase II evaluation of the combination in patients with inoperable non-small
Autor:
Nessa Carey
Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company and a substantial number of biotechnology companies targeting epigenetic processes to treat diseases ranging from cancer to Huntington's