Zobrazeno 1 - 10
of 1 053
pro vyhledávání: '"C N, Pace"'
Publikováno v:
Molecular Biology. 49:933-938
Autor:
Andreas Koschinski, Vladimir A. Mitkevich, C. N. Pace, Alexander A. Makarov, Olga N. Ilinskaya
Publikováno v:
Молекулярная биология. 49:1041-1047
Bacterial ribonucleases (RNases) are considered to be potential anticancer agents. One of most important determinants of RNase cytotoxicity is the net charge of the molecule. In this work a set of mutants of the RNase from Streptomyces aureofaciens (
Autor:
Zhang, Yingjie1, Mi, Jiafei1, Wu, Weilin1, Fei, Jie1, Lv, Bochen1, Yu, Xuezhi1, Wen, Kai1, Shen, Jianzhong1 sjz@cau.edu.cn, Wang, Zhanhui1 wangzhanhui@cau.edu.cn
Publikováno v:
Advanced Science. 8/21/2024, Vol. 11 Issue 31, p1-12. 12p.
Publikováno v:
The FASEB Journal. 10:75-83
For 35 years, the prevailing view has been that the hydrophobic effect is the dominant force in protein folding. The importance of hydrogen bonding was always clear, but whether it made a net favorable contribution to protein stability was not. Studi
Publikováno v:
Protein Science. 4:2411-2423
The molar absorption coefficient, epsilon, of a protein is usually based on concentrations measured by dry weight, nitrogen, or amino acid analysis. The studies reported here suggest that the Edelhoch method is the best method for measuring epsilon f
Publikováno v:
Protein Science. 4:2138-2148
Denaturant m values, the dependence of the free energy of unfolding on denaturant concentration, have been collected for a large set of proteins. The m value correlates very strongly with the amount of protein surface exposed to solvent upon unfoldin
Autor:
Yu, Yueh‐Hsiang1 (AUTHOR) yuehhsiang.yu@immunwork.com, Tian, Wei‐Ting1 (AUTHOR), Grauffel, Cédric1 (AUTHOR), Lin, Wei‐Chen1 (AUTHOR), Hsieh, Ming‐Yu1 (AUTHOR), Wu, Pei‐Wen1 (AUTHOR), Lee, Hui‐Ju1 (AUTHOR), Peng, Chi‐Jiun1 (AUTHOR), Lin, Pei‐Hsuan1 (AUTHOR), Chu, Hsing‐Mao1 (AUTHOR), Lim, Carmay2 (AUTHOR), Chang, Tse Wen1 (AUTHOR) tsewen.chang@immunwork.com
Publikováno v:
Advanced Science. 5/28/2024, Vol. 11 Issue 20, p1-16. 16p.
Publikováno v:
Biochemistry. 32:6152-6156
The rate of hydrogen bond formation at individual amino acid residues in ribonuclease T1 (RNase T1) has been investigated by the hydrogen-deuterium exchange-2D NMR (HDEx-2D NMR) technique (Udgaonkar & Baldwin, 1988; Rder et al., 1988) to gain insight
Publikováno v:
ChemInform. 22
Autor:
Wilson CJ; Department of Mathematics, The University of Western Ontario, London, Ontario, Canada.; Centre for Advanced Materials and Biomaterials Research (CAMBR), The University of Western Ontario, London, Ontario, Canada.; Computational Biomolecular Dynamics Group, Department of Theoretical and Computational Biophysics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., de Groot BL; Computational Biomolecular Dynamics Group, Department of Theoretical and Computational Biophysics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Gapsys V; Computational Biomolecular Dynamics Group, Department of Theoretical and Computational Biophysics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Computational Chemistry, Janssen Research & Development, Beerse, Belgium.
Publikováno v:
Journal of computational chemistry [J Comput Chem] 2024 Jun 30; Vol. 45 (17), pp. 1444-1455. Date of Electronic Publication: 2024 Mar 12.