Zobrazeno 1 - 10
of 30
pro vyhledávání: '"C N, Hall"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The hippocampus is particularly sensitive to hypoxia but it has been difficult to study blood flow in this region. Here the authors compare the neurovascular function of the hippocampus and cortex and in awake mice, and find differences associated wi
Externí odkaz:
https://doaj.org/article/21d36d371cfd4d39a816b085ad27ce2b
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/8da88a6fe35146ec8ceb069fc040f80a
Autor:
Daniella C. N. Hall, Ralf A. Benndorf
Publikováno v:
Cellular and Molecular Life Sciences. 79
PIK3CA mutations are amongst the most prevalent somatic mutations in cancer and are associated with resistance to first-line treatment along with low survival rates in a variety of malignancies. There is evidence that patients carrying PIK3CA mutatio
This book deals with the forensic application of the MMPI, has been written by experts in the various areas covered, and reviews the whole field critically. The book covers areas such as competency to stand trial, criminal responsibility, injury liti
Autor:
H. A. Billson, Kathryn L. Harrison, C. N. Hall, Geoffrey P. Margison, Andrew C. Povey, N. P. Lees
Publikováno v:
Carcinogenesis. 30:615-620
Components of human diets may influence the incidence of colorectal adenomas, by modifying exposure or susceptibility to DNA-damaging alkylating agents. To examine this hypothesis, a food frequency questionnaire was used to assess the diet of patient
Autor:
M. J. Guppy, C N Hall, P. E. Jackson, Geoffrey P. Margison, Andrew C. Povey, Peter J O'Connor, Donald P. Cooper, Alaa Badawi
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 495:103-115
There is increasing evidence that alkylating agent exposure may increase large bowel cancer risk and factors which either alter such exposure or its effects may modify risk. Hence, in a cross-sectional study of 78 patients with colorectal disease, we
Publikováno v:
International Journal of Cancer. 85:68-72
O6-Alkylguanine-DNA-alkyltransferase (ATase) is an important modulator of alkylating agent–induced toxicity and carcinogenicity, but those factors which influence the expression of this repair protein in human tissues are poorly characterised. In t
Autor:
C. N. Hall, Peta E. Jackson, Geoffrey P. Margison, Andrew C. Povey, Donald P. Cooper, Peter J O'Connor
Publikováno v:
Carcinogenesis. 18:1299-1302
O6-alkylguanine DNA-alkyltransferase (ATase) provides protection against the toxic, mutagenic and carcinogenic effects of alkylating agents, principally by removing the promutagenic lesion O6-alkylguanine from DNA. Differences in ATase activity in hu
Autor:
W. L. Marshall, G. C. N. Hall
Publikováno v:
Sexual Abuse: A Journal of Research and Treatment. 7:205-219
Autor:
Geoffrey P. Margison, C N Hall, Elizabeth Hill, Kathryn L. Harrison, Andrew C. Povey, N. P. Lees
Publikováno v:
British Journal of Cancer
In a systematic study of O6-alkylguanine DNA-alkyltransferase activity in the human colon and rectum, tumours were found to occur in regions of low activity. These results are consistent with the hypothesis that O6-alkylguanine DNA-alkyltransferase l